Frontiers in Drug Design and Discovery

Volume 4

by

Atta-ur-Rahman, Gary W. Caldwell, Mohammad Iqbal Choudhary , Zhengyin Yan

DOI: 10.2174/97816080520281090401
eISBN: 978-1-60805-202-8, 2009
ISBN: 978-1-60805-526-5
ISSN: 1574-0889

  
  




Frontiers in Drug Design and Discovery is a book series devoted to publishing the latest and the most important advances in drug desig...[view complete introduction]
PDF US $
- Single user / Non-Library usage: 44
- Multi user / Library usage: 176
Print-On-Demand (P.O.D): *215
Special Offer for Single user / Non-Library usage (PDF + P.O.D): *237

*(Excluding Mailing and Handling)
Purchase: Book Chapters
Download Flyers

Table of Contents

Editorial: Biopharmaceutical & Pharmacokinetic Considerations in Drug Design & Discovery , Pp. i-iii (3)

Atta-ur-Rahman, Gary W. Caldwell, M. Iqbal Choudhary and Zhengyin Yan
Download Free

Present and Future Mass Spectrometry-Based Approaches for Exploratory Drug Metabolism and Pharmacokinetic Studies , Pp. 1-22 (22)

Yunsheng Hsieh
Purchase Chapter

Glutathione Transferases in Drug Discovery and Development: Towards Safer and Efficacious Drugs , Pp. 23-42 (20)

Katholiki Skopelitou, Dimitris Platis, Irene Axarli and Nikolaos E. Labrou
Purchase Chapter

New Sampling Techniques for Pharmacokinetic- Pharmacodynamic Modeling , Pp. 43-80 (38)

Christian Höcht, Marcos Mayer, Javier A.W. Opezzo, Guillermo F. Bramuglia and Carlos A. Taira
Purchase Chapter

Role of Inflammatory Biomarkers in Establishing PK/PD Relationships and Target Organ Toxicity , Pp. 81-96 (16)

Sivaram Pillarisetti and Ish Khanna
Purchase Chapter

Important Drug Interactions for Clinical Oncologists , Pp. 97-121 (25)

Hiroshi Ishiguro, Ikuko Yano and Masakazu Toi
Purchase Chapter

Pharmacogenomic Considerations in Breast Cancer Management , Pp. 122-134 (13)

Hiroshi Ishiguro, Ikuko Yano and Masakazu Toi
Download Free

More Than Skin Deep: The Human Skin Tissue Equivalent as an Advanced Drug Discovery Tool , Pp. 135-161 (27)

Alexandra S. Bause, Sarah D. Lamore and Georg T. Wondrak
Purchase Chapter

Across Skin Barrier: Known Methods, New Performances , Pp. 162-188 (27)

Krzysztof Cal
Purchase Chapter

The Tape Stripping Method as a Valuable Tool for Evaluating Topical Applied Compounds , Pp. 189-227 (39)

J.J. Escobar-Chávez, L.M. Melgoza-Contreras, M. López-Cervantes, D. Quintanar-Guerrero and A. Ganem-Quintanar
Purchase Chapter

Methylphenidate Extended-Release Capsules: A New Formulation for Attention-Deficit Hyperactivity Disorder , Pp. 228-246 (19)

Pilar García-García, Francisco López-Muñoz, Juan D. Molina, Roland Fischer and Cecilio Alamo
Purchase Chapter

Osmotic-Controlled Release Oral Delivery System (OROS® Technology) in Chronic Pain Management , Pp. 247-272 (26)

Flaminia Coluzzi and Consalvo Mattia
Purchase Chapter

Drug Delivery Systems Prepared by Membrane Emulsification , Pp. 273-290 (18)

C. Charcosset and H. Fessi
Purchase Chapter

In Silico ADME Approaches , Pp. 291-332 (42)

Nuria E. Campillo and Juan A. Páez
Purchase Chapter

Advances in ADMET Predictions and Modeling: Rapid Drug Discovery Efforts in 21st Centuries , Pp. 333-350 (18)

Mahmud Tareq Hassan Khan
Purchase Chapter

Computational Intelligence Methods for ADMET Prediction , Pp. 351-377 (27)

David Hecht and Gary B. Fogel
Download Free

Data Modeling and Chemical Interpretation of ADME Properties Using Regression and Rule Mining Techniques , Pp. 378-428 (51)

Kiyoshi Hasegawa and Kimito Funatsu
Purchase Chapter

A Review on Virtual Reality and Haptics Approaches in Drug Design and Discovery , Pp. 429-453 (25)

Susana K. Lai-Yuen
Purchase Chapter

Contributors , Pp. 454-457 (4)

Atta-ur-Rahman
Download Free

List of Contributors

Co-Editor(s):
Prof. Atta-ur-Rahman FRS
H.E.J Research Institute of Chemistry, International Center for Chemical Sciences, University of Karachi
Karachi, 75270
Pakistan


Gary W. Caldwell
Johnson & Johnson Pharmaceutical Research & Development LLC
Welsh & McKean Roads, PO Box 776
Spring House
PA , 19477
USA


Mohammad Iqbal Choudhary
H.E.J. Research Institute of Chemistry, International Center for Chemical Sciences, University of Karachi
Karachi , 75270
Pakistan


DR. Zhengyin Yan
Johnson & Johnson Pharmaceutical Research & Development LLC
Welsh & McKean Roads, P.O. Box 776
Spring House
PA , 19477
USA




Contributor(s):
C. Alamo
Department of Pharmacology, Faculty of Medicine
University of Alcalá
Madrid
Spain


I. Axarli
Laboratory of Enzyme Technology, Department of Agricultural Biotechnology
Agricultural University of Athens
75 Iera Odos Street
Athens
GR, 11855
Greece


A.S. Bause
University of Arizona, College of Pharmacy, Arizona Cancer Center
Tucson
AZ
USA


G.F. Bramuglia,
Cátedra de Farmacología, Facultad de Farmacia y Bioquímica
Universidad de Buenos Aires
Junín 956, (C1113AAD)
Buenos Aires
Argentina


K. Cal
Department of Pharmaceutical Technology
Medical University of Gdansk
Hallera 107
Gdansk, 80-416
Poland


N.E. Campillo
Instituto de Química Médica (CSIC)
Juan de la Cierva, nº 3
Madrid, 28006
Spain


C. Charcosset
Laboratoire d'Automatique et de Génie des Procédés, Université de Lyon
UMR CNRS 5007, ESCPE-Lyon, 43 Bd du 11 Novembre 1918
Villeurbanne Cedex, 69 622
France


F. Coluzzi
I.C.O.T. - Polo Pontino, Dept. Anaesthesiology, Intensive Care Medicine and Pain Therapy
University of Rome "La Sapienza"
Rome
Italy


J.J. Escobar-Chávez
División de Estudios de Posgrado (Tecnología Farmacéutica), Facultad de Estudios Superiores Cuautitlán
Universidad Nacional Autónoma de México, Cuautitlán Izcalli
Estado de México, 54740
México


H. Fessi
Laboratoire d'Automatique et de Génie des Procédés
Université de Lyon
UMR CNRS 5007, ESCPE-Lyon, 43 Bd du 11 Novembre 1918
Villeurbanne Cedex, 69622
France


R. Fischer
Medice chem.-phar., Fabrik Pütter GmbH & Co.KG
Iserlohn
MI
Germany


G.B. Fogel
Natural Selection, Inc.
9330 Scranton Rd.
San Diego
CA , 92121
USA


K. Funatsu
Kamakura Research Laboratories, Chugai Pharmaceutical Co., LTD
200 Kajiwara, Kamakura
Kanagawa, 247-8530
Japan


A. Ganem-Quintanar
División de Estudios de Posgrado (Tecnología Farmacéutica), Facultad de Estudios Superiores Cuautitlán
Universidad Nacional Autónoma de México, Cuautitlán Izcalli
Estado de México, 54740
México


P. García-García
Department of Pharmacology, Faculty of Medicine
University of Alcalá
Madrid
Spain


K. Hasegawa
Department of Chemical System Engineering
The University of Tokyo
Hongo 7-3-1, Bunkyo-ku
Tokyo, 113- 8656
Japan


D. Hecht
Southwestern College
900 Otay Lakes Rd., Chula Vista
Mantova
CA , 91910
USA


C. Höcht
Cátedra de Farmacología, Instituto de Fisiopatología y Bioquímica Clínica, Facultad de Farmacia y Bioquímica
Universidad de Buenos Aires, Junín 956, (C1113AAD)
Buenos Aires
Argentina


Y. Hsieh
Department of Drug Metabolism and Pharmacokinetics, Schering-Plough Research Institute
2015 Galloping Hill Road, K-15-3700
Kenilworth
NJ , 07033
USA


H. Ishiguro
Department of Clinical Trial Management / Outpatient Oncology
Kyoto Univercity Hospital, Translational Research Center
Unit, 54 Shogoinkawaharara-cho, Sakyo-Ku
Kyoto-City, 606-8507
Japan


M.T.H. Khan
Department of Pharmacology, Institute of Medical Biology, Faculty of Medicine
University of Tromsø
Tromsø, 9037
Norway


I. Khanna
Reddy US Therapeutics Inc., 3065 Northwoods Circle, ,
Norcross
GA , 30071
USA


N.E. Labrou
Laboratory of Enzyme Technology, Department of Agricultural Biotechnology
Agricultural University of Athens
75 Iera Odos Street
Athens
GR, 11855
Greece


S.K. Lai-Yuen
Department of Industrial & Management Systems Engineering
University of South Florida, Tampa
FL , 33620-5350
USA


S.D. Lamore
University of Arizona, College of Pharmacy, Arizona Cancer Center
Tucson
AZ
USA


M. López-Cervantes
División de Estudios de Posgrado (Tecnología Farmacéutica), Facultad de Estudios Superiores Cuautitlán
Universidad Nacional Autónoma de México, Cuautitlán Izcalli
Estado de México, 54740
México


F. López-Muñoz
Department of Pharmacology, Faculty of Medicine
University of Alcalá
Madrid
Spain


C. Mattia
I.C.O.T. - Polo Pontino, Dept. Anaesthesiology, Intensive Care Medicine and Pain Therapy
University of Rome "La Sapienza"
Rome
Italy


M. Mayer
Cátedra de Farmacología, Instituto de Fisiopatología y Bioquímica Clínica, Facultad de Farmacia y Bioquímica,
Universidad de Buenos Aires
Junín 956, (C1113AAD)
Buenos Aires
Argentina


L.M. Melgoza-Contreras
Departamento de Sistemas Biológicos, Universidad Autónoma Metropolitana-Xochimilco
Calzada del Hueso 1100, Colonia Villa Quietud, México D.F.
México


J.D. Molina
Acute Inpatients Unit, Dr. Lafora Psychiatric Hospital
Madrid
Spain


J.A.W. Opezzo
Cátedra de Farmacología, Instituto de Fisiopatología y Bioquímica Clínica, Facultad de Farmacia y Bioquímica
Universidad de Buenos Aires, Junín 956, (C1113AAD)
Buenos Aires
Argentina


J.A. Páez
Instituto de Química Médica (CSIC)
Juan de la Cierva, 3
Madrid, 28006
Spain


S. Pillarisetti
Reddy US Therapeutics Inc.
3065 Northwoods Circle
Norcross
GA , 30071
USA


D. Platis
Laboratory of Enzyme Technology, Department of Agricultural Biotechnology, Agricultural University of Athens
75 Iera Odos Street
Athens
GR, 11855
Greece


D. Quintanar-Guerrero
División de Estudios de Posgrado (Tecnología Farmacéutica), Facultad de Estudios Superiores Cuautitlán
Universidad Nacional Autónoma de México, Cuautitlán Izcalli
Estado de México, 54740
México


K. Skopelitou
Laboratory of Enzyme Technology, Department of Agricultural Biotechnology
Agricultural University of Athens
75 Iera Odos Street
Athens
GR, 11855
Greece


C.A. Taira
Cátedra de Farmacología, Instituto de Fisiopatología y Bioquímica Clínica, Facultad de Farmacia y Bioquímica
Universidad de Buenos Aires, Junín 956, (C1113AAD)
Buenos Aires
Argentina


M. Toi
Kyoto Univercity Hospital, Breast Surgery Department, 54 Shogoinkawaharara-cho, Sakyo-ku
Kyoto-city, 606-8507
Japan


G.T. Wondrak
University of Arizona, College of Pharmacy, Arizona Cancer Center
Tucson
AZ
USA


I. Yano
Kyoto Univercity Hospital, Department of Pharamcy
54 Shogoinkawaharara-cho, Sakyo-ku
Kyoto-city, 606-8507
Japan




Advertisement


Webmaster Contact: urooj@benthamscience.org Copyright © 2014 Bentham Science