Chapter 6

Nature as Source and Inspiration for the Synthesis of New Anticancer Drugs

Daniele Passarella, Alessandra Giardini, Giordano Lesma, Alessandra Silvani and Bruno Danieli

Abstract

<p>The bifunctional taxoid-colchicinoid hybrids were synthesised and evaluated in assays of cytotoxicity and tubulin assembly/disassembly. All compounds showed a high degree of cytotoxicity.</p>

Total Pages: 51-54 (4)

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