Beta-glucan, Structure, Chemistry and Specific Application

Book Series: Biology and Chemistry of Beta Glucan

Volume 2

by

Vaclav Vetvicka, Miroslav Novak

DOI: 10.2174/97816080526081130201
eISBN: 978-1-60805-260-8, 2013
ISBN: 978-1-60805-301-8
ISSN: 2211-0526 (Print)



Indexed in: EBSCO, Ulrich's Periodicals Directory.

Despite of the efforts of pharmaceutical researchers to find new medicaments, nature offers many substances with healing properties—be...[view complete introduction]

Chemical Synthesis of Oligo-(1→3)-β-D-Glucans

- Pp. 83-101 (19)

Vincent Ferrières, Laurent Legentil, Balla Sylla, Karine Descroix, Caroline Nugier-Chauvin and Richard Daniellou

Abstract

The synthesis of β-(1→3)-glucans is at present has more than a chemical challenge. The discovery of their biological properties found development for new anticancer therapies, the efficient preparation of pure and structurally well-defined β-(1→3)-glucans has generated interest in the glycochemist community. This chapter highlights recent strategies that not only yielded the target biomolecules but have also drawn attention on basic limitations. It also shows how it is possible to strengthen the activity of β-glucans by conjugation to non saccharidic derivatives.

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