Functional Molecular Imaging In Hepatology


by

Susanne Keiding, Michael Sørensen

DOI: 10.2174/97816080529051120101
eISBN: 978-1-60805-290-5, 2012
ISBN: 978-1-60805-677-4





The eBook discusses how the special physiology of the liver must be considered when applying functional molecular imaging in hepatolog...[view complete introduction]
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Metabonomic Analysis in Liver Diseases

- Pp. 76-86 (11)

Laia Chavarria, Ignasi Barba and Juan Córdoba

Abstract

Metabonomics is a new technology that provides rapid, accurate and precise analysis of a large number of metabolites in biological systems. Using multivariate analysis and pattern recognition, it provides a direct unbiased measure of biochemical consequences of pathology or drug treatment. The integration of the all ‘omics’ information (genomics, transcriptomics, proteomics and metabonomics) can provide knowledge for better understanding of biological systems and may lead to the generation of new mechanistic hypotheses to explain the development of pathologies. In this chapter, we will give an overview of the basic principles of this new technology and provide examples of applications in liver diseases.

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