Dimorphic Fungi: Their Importance as Models for Differentiation and Fungal Pathogenesis


by

José R.-Herrera

DOI: 10.2174/97816080536431120101
eISBN: 978-1-60805-364-3, 2012
ISBN: 978-1-60805-510-4



Recommend this eBook to your Library

Indexed in: Scopus

Dimorphism can be defined as the property of different fungal species to grow in the form of budding yeasts or in the form of mycelium...[view complete introduction]

Table of Contents

Foreword

- Pp. i

Rafael Sentandreu

Download Free

Preface

- Pp. ii

José Ruiz-Herrera

Download Free

List of Contributors

- Pp. iii-iv (2)

José Ruiz-Herrera

Download Free

An Introduction to Fungal Dimorphism

- Pp. 3-15 (13)

José Ruiz-Herrera and Eduardo Campos-Góngora

View Abstract Purchase Chapter

Paracoccidioides, One Genus, More Than One Species: P. brasiliensis Cryptic Species and P. lutzii. Dimorphism, Morphogenesis, Phylogeny

- Pp. 16-34 (19)

Gioconda San-Blas and Gustavo Niño-Vega

View Abstract Purchase Chapter

Dimorphism and Pathogenicity of the Opportunistic Ascomycota Candida albicans

- Pp. 35-45 (11)

Margarita Rodríguez-Kessler, María de la Luz Guerrero-González and Juan Francisco Jiménez-Bremont

View Abstract Purchase Chapter

Histoplasma capsulatum and its Virulence Determinants

- Pp. 46-57 (12)

Amalia Porta, Elena Calabrese, Ilaria Granata and Bruno Maresca

View Abstract Purchase Chapter

Development and Dimorphism of the Yeast Yarrowia lipolytica

- Pp. 58-66 (9)

Juan Francisco Jiménez-Bremont, Aída Araceli Rodríguez-Hernández and Margarita Rodríguez-Kessler

View Abstract Purchase Chapter

Sporothrix schenckii and General Aspects of Sporotrichosis

- Pp. 67-86 (20)

Leila M. Lopes-Bezerra and Rosana C. Nascimento

View Abstract Purchase Chapter

Yeast-Hypha Dimorphism in Zygomycetous Fungi

- Pp. 87-104 (18)

V. Ghormade, E. Pathan and M. V. Deshpande

View Abstract Purchase Chapter

Development and Dimorphism of the Phytopathogenic Basidiomycota Ustilago maydis

- Pp. 105-116 (12)

José Ruiz-Herrera and Claudia G. León-Ramírez

View Abstract Purchase Chapter

Index

- Pp. 117-143 (27)

José Ruiz-Herrera

Download Free

Foreword

“Fungal dimorphism” refers to the ability of some fungal species to grow under two morphological forms, feature that has fascinated the scientists for almost a Century. The original interest in fungal dimorphism was associated to pathogenesis but it is now clear that it implies something much more important than the exclusive study of the final morphology of the fungal cells. The original definition overlooks the importance of dimorphism as a process of cellular differentiation. We can inquire which mechanisms are involved in the morphological changes and the possibilities are that certain genes are expressed only in a specific morphology or that the gene products are assembled in the cell wall in a different way to give an alternative molecular architecture. Only an in deep understanding of the processes involved in dimorphism will be possible with development of a wide-ranging list of experimental procedures combined together with the new genetic techniques, the rapid access to genomic information and bioinformatic analyses of many of these fungal species. It can be said that the new information collected literally forged a new frontier of research for understanding the molecular nature and the control of the fungal dimorphism. The aim of this eBook is to present in a single volume a review as current as possible of dimorphism among fungi. It addresses the actual state of art on relevant aspects of dimorphism in a few fungal species by different authors as it is increasingly clear that reviewing this subject adequately is probably beyond the capability of a single author. The text is organized in a way that attempts to enhance readability and should be of interest not only to those doing research in this specific area (including detection of potential targets for development of new antifungal drugs), but also to those interested in other aspects of fungal cells and for those in general biology.

Rafael Sentandreu
Facultat de Farmacia
Universitat de Valencia
España


Preface

Dimorphism is the property of different fungal species to grow as budding yeasts or mycelium depending on the environmental conditions. Dimorphism involves extensive changes in cell physiology and morphology in response to external signals, making this phenomenon a superb model for the study of the differentiation processes occurring in eukaryotic organisms. Additionally, it must be pointed out that the most important human and some plant pathogenic fungi are dimorphic, displaying different morphologies when growing as saprophytes, or inside their hosts, suggesting that this process may be an ideal target for the design of efficient antimycotic drugs.

Much information of the molecular bases of the dimorphic transition in fungi has been generated in recent years, and the important advances in this important subject in the most widely studied fungal species are presented and discussed in this volume by different specialists with a well gained reputation in the field.

I am certain that the contents of this eBook will be an important source of information to all the scholars working or interested in human, animal and plant pathogenesis; fungal genetics, molecular biology and development; evolution, and cell differentiation.

José Ruiz-Herrera Unidad Irapuato
Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional
Irapuato, Gto.
México

List of Contributors

Editor(s):
José R.-Herrera
Unidad Irapuato
Centro de Investigación y de Estudios Avanzados
del IPN
Irapuato
Gto.
México




Contributor(s):
E. Campos-Góngora
Departamento de Ingeniería Genética
Unidad Irapuato
Centro de Investigación y de Estudios Avanzados del IPN1

/
Centro de Investigación en Nutrición y Salud Pública
Universidad Autónoma de Nuevo León2
Monterrey, NL México
Km. 9.6 Libramiento Norte Carretera Irapuato-León
Apartado Postal 629



E. Calabrese
Dept. of Pharmaceutical and Biomedical Science
University of Salerno
Italy


MV. Deshpande
Biochemical Sciences Division
National Chemical Laboratory
Pune, 411008
India


V. Ghormade
Centre for Nanobioscience
Agharkar Research Institute
Pune, 411004
India


I. Granata
Dept. of Pharmaceutical and Biomedical Science
University of Salerno
Italy


M de la L. Guerrero-González
División de Biología Molecular
Instituto Potosino de Investigación Cientifica y Tecnológica (IPICYT)
San Luis Potosí
México
/
Camino a la Presa de San José 2055
Apartado Postal 3-74 Tangamanga
San Luis Potosí, SLP, C.P. 78216
México


JF. Jiménez-Bremont
División de Biología Molecular
Instituto Potosino de Investigación Cientifica y Tecnológica (IPICYT)
San Luis Potosí
México
/
Camino a la Presa de San José 2055
Apartado Postal 3-74 Tangamanga
San Luis Potosí, SLP, C.P. 78216
México


CG. León-Ramírez
Departamento de Ingeniería Genética
Unidad Irapuato. Centro de Investigación y de Estudios Avanzados del IPN
México
/
Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional
Km. 9.6 Libramiento Norte Carretera Irapuato-León
Apartado Postal 629



LM. Lopes-Bezerra
Laboratory of Cellular Mycology and Proteomics
Biology Institute, State University of Rio de Janeiro (UERJ)
Rua São Francisco Xavier 524 PHLC
Rio de Janeiro, 20550-013
Brazil


B. Maresca
Dept. of Pharmaceutical and Biomedical Science
University of Salerno
Italy


RC. Nascimento
Laboratory of Cellular Mycology and Proteomics
Biology Institute, State University of Rio de Janeiro (UERJ)
Rua São Francisco Xavier 524 PHLC
Rio de Janeiro, 20550-013
Brazil


G. Niño-Vega
Laboratorio de Micología, Centro de Microbiología y Biología Celular
Instituto Venezolano de Investigaciones Científicas (IVIC)
Apartado 20632
Caracas, 1020A
Venezuela


E. Pathan
Biochemical Sciences Division
National Chemical Laboratory
Pune, 411008
India


AA. Rodríguez-Hernández
División de Biología Molecular
Instituto Potosino de Investigación Cientifica y Tecnológica (IPICYT)
San Luis Potosí
México
/
Camino a la Presa de San José 2055
Apartado Postal 3-74 Tangamanga
San Luis Potosí, SLP, C.P. 78216
México


M. Rodríguez-Kessler
Facultad de Ciencias
Universidad Autónoma de San Luis Potosí
México
/
Av. Salvador Nava s/n
Zona Universitaria
San Luis Potosí, SLP, C.P. 78290
México


J. Ruiz-Herrera
Departamento de Ingeniería Genética
Unidad Irapuato. Centro de Investigación y de Estudios Avanzados del IPN
México
/
Km. 9.6 Libramiento Norte Carretera Irapuato-León
Apartado Postal 629



G. San-Blas
Laboratorio de Micología, Centro de Microbiología y Biología Celular
Instituto Venezolano de Investigaciones Científicas (IVIC)
Apartado 20632
Caracas, 1020A
Venezuela




Reviews

“…an ideal book for scholars and researchers working or interested in human, animal and plant pathogenesis, fungal genetics, molecular biology, development, evolution, and differentiation.”


Fungal Diversity (Springer), Volume 59, Issue 1, March 2013


“The book is well-presented and edited, with some excellent photographs... …It will surely become a benchmark in the synthesis of our understanding of the dimorphism phenomenon in human pathogenic fungi.”


IMA Fungus, Volume 4, No.1, June 2013


Advertisement


Related Journals



Related Books



Webmaster Contact: urooj@benthamscience.org Copyright © 2016 Bentham Science