Chapter 17

Roles of Inositol & Inositol Phosphates in Immunity, Infection and Inflammation

A.K.M. Shamsuddin and Guang-Yu Yang

Abstract

InsP<sub>6</sub> with or without inositol enhances NK cell activity and stimulates polymorphonuclear cell priming function and the macrophages to produce cytokines. InsP<sub>6</sub> can inhibit human immunodeficiency virus (HIV) replication; both InsP5 and InsP<sub>6</sub> are critical in HIV particle assembly. InsP<sub>6</sub> plays significant roles in mucosal protection in the gastrointestinal tract, and inflammation.

Total Pages: 216-226 (11)

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