Comprehensive Practical Hepatology


by

Yukihiro Shimizu

DOI: 10.2174/97816810820591160101
eISBN: 978-1-68108-205-9, 2016
ISBN: 978-1-68108-206-6



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Acute and chronic liver disease is a global endemic healthcare concern. More than 500 million people around the world are infected wit...[view complete introduction]

Table of Contents

Foreword

- Pp. i

Nobuyuki Enomoto

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Preface

- Pp. iii

Yukihiro Shimizu

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List of Contributors

- Pp. v

Yukihiro Shimizu

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Symptoms and Signs Suggestive of Liver Disease

- Pp. 3-27 (25)

Masami Minemura

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Diagnostic Strategies for Patients with Abnormal Liver Function Tests

- Pp. 29-47 (19)

Masami Minemura

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Approach to Patients with Acute Liver Injury

- Pp. 49-76 (28)

Yasuhiro Nakayama and Yukihiro Shimizu

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Approach to Patients with Chronic Liver Injury

- Pp. 77-120 (44)

Yukihiro Shimizu

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Diagnostic Strategies and Treatment of Liver Tumors

- Pp. 121-146 (26)

Yoshiharu Tokimitsu and Yukihiro Shimizu

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Liver Function Abnormalities in Systemic Disease

- Pp. 147-155 (9)

Yukihiro Shimizu

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Sytemic Abnormalities in Liver Disease

- Pp. 157-164 (8)

Yukihiro Shimizu and Masami x Masami Minemura

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Infection and Liver

- Pp. 165-175 (11)

Kazuto Tajiri

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Approach to Liver Injury Caused by Drugs and Toxins

- Pp. 177-191 (15)

Kazuto Tajiri and Yukihiro Shimizu

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Risk of Surgery and Drug Therapy in Patients with Liver Disease

- Pp. 193-198 (6)

Yukihiro Shimizu

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Approach to Children with Abnormal Liver Function Tests Results

- Pp. 199-213 (15)

Masami Minemura

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Practical Management of Elderly Patients with Liver Injury

- Pp. 215-220 (6)

Kazuto Tajiri

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Practical Management of Pregnant Women with Liver Injury

- Pp. 221-228 (8)

Kazuto Tajiri

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Lifestyle Recommendation for Patients with Liver Diseases

- Pp. 229-236 (8)

Kazuto Tajiri

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Medical Management of Patients Following Liver Transplantation

- Pp. 237-258 (22)

Yasuhiro Nakayama and Yukihiro Shimizu

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Subject Index

- Pp. 259-261 (3)

Yukihiro Shimizu

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Foreword

First of all, I am honored to introduce this exciting book. Dr. Shimizu has been involved in hepatology for over 30 years and has studied hepatology in the United States twice. On the first occasion at the age of 30 years old, he joined the Pittsburgh Cancer Institute, where he undertook research for 2 years on tumor immunology in human liver tumors as part of the laboratory of Dr. Theresa L. Whiteside and published 6 papers with her. When he was 36 years old, he joined the Scripps Research Institute, and studied immunology of viral hepatitis under the guidance of Dr. Francis V. Chisari. Since returning to his home university (Toyama Medical and Pharmaceutical University), he has been engaged in clinical and basic research and presented many papers at domestic and international hepatology meetings, that have been published in international journals. Since I became involved in molecular analysis of hepatitis virus, I have had the opportunity to meet him several times at various meetings and discussions on hepatology research.

In 2006, he left the Toyama Medical and Pharmaceutical University, and started a new career as a clinical specialist of hepatology. He is now the Director of Nanto Municipal Hospital at which several general physicians work alongside organ specialists. He believes the role of general physicians in liver disease will become more important as the proportion of elderly in the population increases. Many patients with liver injury will first see their general physician and the role of general physicians will increase in the management of patients with liver diseases. Although there are many books on hepatology most are aimed at hepatologists with few books on liver disease focusing on primary care management performed by general physicians. I believe that this e-Book will be a very helpful and practical guide for general physicians.

Nobuyuki Enomoto
Professor, First Department of Internal Medicine
University of Yamanashi
Japan


Preface

More than 500 million people are infected with hepatitis B or hepatitis C virus, and 500,000 patients with hepatocellular carcinoma die every year. Therefore, a provision for those patients is an urgent and important issue worldwide. Although promising therapies have been developed for hepatitis viral infection, management of liver cirrhosis, and hepatocellular carcinoma, many patients may not have received them if they were not examined by hepatologists. As many patients with liver function disorder first consult non-hepatologist clinicians or general physicians, enlightenment of primary care physicians concerning early management of liver disease is important for eradication of viral hepatitis infection and eventually hepatocellular carcinoma. In this e-Book, I would like to provide a current standard guideline for primary care or early management of patients with liver function abnormalities, who are often seen in daily practice. This book provides practical advice on management of liver disease to non-hepatologists and general physicians for better treatment and prognosis of patients with liver diseases as achieved by hepatologists

Yukihiro Shimizu
Director, Gastroenterology Center
Nanto Municipal Hospital
Toyama
Japan

List of Contributors

Editor(s):
Yukihiro Shimizu
Nanto Municipal Hospital
Toyama
Japan




Contributor(s):
Masami Minemura
University of Toyama
The Third Department of Internal Medicine
Toyama
Japan


Yasuhiro Nakayama
University of Yamanashi
The First Department of Internal Medicine
Yamanashi
Japan


Yukihiro Shimizu
Gastroenterology Center
Nanto Municipal Hospital
Toyama
Japan


Yoshiharu Tokimitsu
Department of Internal Medicine
Toyama Red Cross Hospital
Toyama
Japan


Kazuto Tajiri
University of Toyama
The Third Department of Internal Medicine
Toyama
Japan




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