Developmental and Stem Cell Biology in Health and Disease


by

Ahmed El-Hashash

DOI: 10.2174/97816810821961160101
eISBN: 978-1-68108-219-6, 2016
ISBN: 978-1-68108-220-2



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Research into stem cells started in the 1960s with experiments on spleen cultures. Evans and Kaufman made a breakthrough in mouse embr...[view complete introduction]

Table of Contents

Preface

- Pp. i

Ahmed El-Hashash

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List of Contributors

- Pp. ii-iii (2)

Ahmed El-Hashash

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Stem Cells, Developmental Biology and Reparative/ Regenerative Medicine: Tools and Hope for Better Human Life

- Pp. 3-5 (3)

Ahmed El-Hashash

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The First Morphogenetic Events During Mammalian Development

- Pp. 6-35 (30)

Manal E. Elsawaf

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Gene and Signals Regulating Stem Cell Fates

- Pp. 36-48 (13)

Mohamed Berika, John Ku, Haifen Huang and Ahmed El-Hashash

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Stem Cell Biology: Flies As Models and Examples

- Pp. 49-81 (33)

Nahla M. Shoukry, Elham M. Youssef Elabd, Hani S. Hafez and Noha M. Osman

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Behavior and Asymmetric Cell Divisions of Stem Cells

- Pp. 82-105 (24)

Sameh Elshahawy, Ahmed R. N. Ibrahim, Salaheldin S. Soliman, Marwa E. Elgayyar and Ahmed El-Hashash

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Adult Stem Cell Niches and Their Regulatory Molecular Mechanisms

- Pp. 106-120 (15)

John Ku, Wadah Alhassen, Haifen Huang, Salaheldin S. Soliman, Ahmed RN Ibrahim and Ahmed HK El-Hashash

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Stem Cell Regulatory Mechanisms During Wound Healing and Cancer

- Pp. 121Chapter-142 (22)

Ahmed RN Ibrahim, Deshna Majmudar, Safia Gilani, Jesse Garcia Castillo and Ahmed El-Hashash

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Stem Cells in Cancer Development and Therapy

- Pp. 143-165 (23)

Azza El Amir and Wajeet Nabil

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Stem Cells and Neurodegenerative Diseases

- Pp. 166-192 (27)

Hanaa H. Ahmed, Hadeer A. Aglan and Ahmed A. Abd-Rabou

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Stem Cells and Bone Disorders

- Pp. 193-209 (17)

Hanaa H. Ahmed, Sara M. Abdo and Ahmed A. Abd-Rabou

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A Scope on Stem Cells and Human Parasites

- Pp. 210-247 (38)

Marwa Adel HasbySaad

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Subject Index

- Pp. 248-249 (2)

Ahmed El-Hashash

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Preface

Stem cell research can be traced back for more than 20 years when scientists first isolated embryonic stem cells from mouse blastocysts, and a research article announcing the discovery of human embryonic stem cells emerged in 1998. Stem cell research field has rapidly expanded as new research and experience broaden our knowledge about different aspects of stem cell biology and applications. In the past decade, the stem cell field has grown very rapidly, and continues to be one of the most exciting aspects of biomedical research. This book brings together a number of topics that are related to stem cell development and behavior as well as stem cell applications in the treatment of different human diseases.

Although we could not hope to be comprehensive in the coverage of stem cells of different tissues, our main aim in compiling this book was to bring together a selection of the current progress in understanding stem cell biology and development as well as potential applications of stem cells in the treatments of different human diseases.

In preparing this book, we aimed at making it accessible to not only those working in stem cell biology field, but also to non-experts with a broad interest in stem cells and in human health. Our hope is that this book will be of value to all concerned with stem cell biology, development and application in medicine.

Ahmed El-Hashash
Children’s Hospital Los Angeles
Keck School of Medicine and Ostrow School of Dentistry
University of Southern California
USA

List of Contributors

Editor(s):
Ahmed El-Hashash
Children’s Hospital Los Angeles
Keck School of Medicine and Ostrow School of Dentistry
University of Southern California
USA




Contributor(s):
Ahmed A. Abd-Rabou
Hormones Department, Medical Research Division
National Research Center
Cairo
Egypt


Ahmed El-Hashash
Stem Cells, Regenerative Medicine and Developmental Biology Program, Children’s Hospital Los Angeles
Keck School of Medicine and Ostrow School of Dentistry, University of Southern California, 4661 Sunset Boulevard
Los Angeles
CA 90027
USA


Ahmed R. N. Ibrahim
Stem Cells, Regenerative Medicine and Developmental Biology Program, Children’s Hospital Los Angeles
Keck School of Medicine and Ostrow School of Dentistry, University of Southern California, 4661 Sunset Boulevard
Los Angeles
CA 90027
USA


Alhassen Wadah
Stem Cells, Regenerative Medicine and Developmental Biology Program, Children’s Hospital Los Angeles
Keck School of Medicine and Ostrow School of Dentistry, University of Southern California, 4661 Sunset Boulevard
Los Angeles
CA 90027
USA


Azza El Amir
Zoology Department, Faculty of Science
Cairo University
Giza
Egypt


Deshna Majmudar
Stem Cells, Regenerative Medicine and Developmental Biology Program, Children’s Hospital Los Angeles
Keck School of Medicine and Ostrow School of Dentistry, University of Southern California, 4661 Sunset Boulevard
Los Angeles
CA 90027
USA


Elham M. Youssef Elabd
National Research Center
Suez University
Suez
Egypt


Hadeer A. Aglan
Hormones Department, Medical Research Division
National Research Center
Cairo
Egypt


Haifen Huang
Stem Cells, Regenerative Medicine and Developmental Biology Program, Children’s Hospital Los Angeles
Keck School of Medicine and Ostrow School of Dentistry, University of Southern California, 4661 Sunset Boulevard
Los Angeles
CA 90027
USA


Hani S. Hafez
Suez University
Suez
Egypt


Hanaa H. Ahmed
Hormones Department, Medical Research Division
National Research Center
Cairo
Egypt


Jesse Garcia Castillo
Stem Cells, Regenerative Medicine and Developmental Biology Program, Children’s Hospital Los Angeles
Keck School of Medicine and Ostrow School of Dentistry, University of Southern California, 4661 Sunset Boulevard
Los Angeles
CA 90027
USA


John Ku
Anatomy Department, Faculty of Medicine
Mansoura University
Mansoura
Egypt
/
Rehabilitation Science Department
College of Applied Medical Sciences, King Saud University
Riyadh
KSA


Manal E. Elsawaf
Faculty of Medicine
Tanta University
Tanta
Egypt


Marwa E. Elgayyar
Stem Cells, Regenerative Medicine and Developmental Biology Program, Children’s Hospital Los Angeles
Keck School of Medicine and Ostrow School of Dentistry, University of Southern California, 4661 Sunset Boulevard
Los Angeles
CA 90027
USA


Mohamed Berika
Anatomy Department, Faculty of Medicine
Mansoura University
Mansoura
Egypt
/
Rehabilitation Science Department
College of Applied Medical Sciences, King Saud University
Riyadh
KSA


Marwa Adel HasbySaad
Faculty of Medicine
Tanta University
Tanta
Egypt


Nahla M. Shoukry
Suez University
Suez
Egypt


Noha M. Osman
National Research Center
Suez University
Suez
Egypt
/
Department of Molecular and Computational biology
University of Southern California
Los Angeles
CA
USA
/
Washington State University
University of Southern California
Pullman
Washington
USA


Safia Gilani
Stem Cells, Regenerative Medicine and Developmental Biology Program, Children’s Hospital Los Angeles
Keck School of Medicine and Ostrow School of Dentistry, University of Southern California, 4661 Sunset Boulevard
Los Angeles
CA 90027
USA


Salaheldin S. Soliman
Stem Cells, Regenerative Medicine and Developmental Biology Program, Children’s Hospital Los Angeles
Keck School of Medicine and Ostrow School of Dentistry, University of Southern California, 4661 Sunset Boulevard
Los Angeles
CA 90027
USA


Sameh Elshahawy
Stem Cells, Regenerative Medicine and Developmental Biology Program, Children’s Hospital Los Angeles
Keck School of Medicine and Ostrow School of Dentistry, University of Southern California, 4661 Sunset Boulevard
Los Angeles
CA 90027
USA


Sara M. Abdo
Chemistry Department, Faculty of Science
Helwan University
Cairo
Egypt


Wajeet Nabil
Zoology Department, Faculty of Science
Cairo University
Giza
Egypt




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