Frontiers in Stem Cell and Regenerative Medicine Research

Volume 3

by

Atta-ur-Rahman , Shazia Anjum

DOI: 10.2174/97816810825781160301
eISBN: 978-1-68108-257-8, 2017
ISBN: 978-1-68108-258-5
ISSN: 2467-9593 (Print)
ISSN: 2352-7633 (Online)



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The third volume of this series features reviews on the use of stem cells in bone repair, neonatal brain injury and esophageal tissue ...[view complete introduction]

Table of Contents

Preface

- Pp. i-ii (2)

Atta-ur-Rahman and Shazia Anjum

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List of Contributors

- Pp. iii

Atta-ur-Rahman and Shazia Anjum

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Stem Cell-Based Therapies for Bony Repair

- Pp. 3-67 (65)

Ryan R. Kelly and Amanda C. LaRue

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Stem Cell Therapy for Brain Injury in Neonates

- Pp. 68-101 (34)

Marisa J. Pacella, Martha Douglas-Escobar, Tong Zheng and Michael D. Weiss

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Models of Hereditary Neurodegenerative, Neurological, and Psychiatric Diseases Based on Induced Pluripotent Stem Cell-Derived Neurons

- Pp. 102-165 (64)

Sergey P. Medvedev and Suren M. Zakian

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Prospects of Regenerative Medicine in the Treatment of Pulmonary Diseases

- Pp. 166-215 (50)

Alexander V. Averyanov

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Esophageal Tissue Engineering

- Pp. 216-246 (31)

Todd Jensen, Wael Sayej and Christine Finck

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Subject Index

- Pp. 247-255 (9)

Atta-ur-Rahman and Shazia Anjum

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Preface

Stem cell and regenerative medicine is a hot area of current research that is expected to have a profound impact on health and medicine. It is moving fast and often people are interested in finding out most contemporary discoveries. It has shown great potential to meet the worldwide organ shortage challenge by tissue regeneration and organ replacement.

The 3rd volume of ‘Frontiers in Stem Cell and Regenerative Medicine Research’ contains reviews written by eminent specialists in major rapidly developing fields of stem cell and regenerative medicine research. LaRue and Kelly have presented the advantages of utilizing various types of stem cells to treat bone related diseases and difficult-to-heal fractures. Pacella et al. have reviewed the current status of stem cell therapy in neonatal brain injury, encompassing hypoxic-ischemic encephalopathy (HIE), perinatal stroke, and white matter injury. This holds promise for improving the methods of diagnosis, prevention and as well as the development of innovative treatments for such injuries.

Neurodegenerative, neurological, and psychiatric diseases (NNPDs) significantly contribute to disability and mortality. Zakian and Medvedev have focused on the cell models based on patient-specific induced pluripotent stem cell derived neurons and their use in the search for new drugs. The utility of genome engineering for the creation and study of cell models for NNPDs is discussed in detail.

Respiratory diseases represent a wide array of common diseases with great social and financial burden. Regenerative medicine could offer new tools for treating severe and progressive lung diseases as depicted in Alexander V. Averyanov’s review. Patients suffering from esophageal defects and disease are commonly treated with surgical intervention, which can lead to a host of short and long term complications including the need for repeated surgery. Finck et al. have covered novel tissue engineering approaches for esophageal defects.

We hope that the readers will enjoy reading about the latest and exciting revolutions in prominent areas of stem cell and regenerative medicine research.

We are grateful to all the authors for their contributions. We are also thankful to the editorial staff of Bentham Science Publishers, particularly Dr. Faryal Sami, Mr. Shehzad Naqvi and Mr. Mahmood Alam for their constant support and great help.

Prof. Atta-ur-Rahman, FRS
Honorary Life Fellow
Kings College
University of Cambridge
Cambridge
UK

&

Dr. Shazia Anjum
Department of Chemistry
Cholistan Institute of Desert Studies
The Islamia University of Bahawalpur
Pakistan

List of Contributors

Editor(s):
Atta-ur-Rahman
Kings College
University of Cambridge
Cambridge
UK


Shazia Anjum
Department of Chemistry
Cholistan Institute of Desert Studies
The Islamia University of Bahawalpur
Pakistan




Contributor(s):
Alexander V. Averyanov
Federal Research Clinical Center under Federal Medical Biological Agency of Russia
Moscow
Russia


Amanda C. LaRue
Research Services
Ralph H. Johnson Veterans Affairs Medical Center
USA
/
Department of Pathology and Laboratory Medicine
Medical University of South Carolina
Charleston
South Carolina


Christine Finck
Connecticut Children’s Medical Center Department of Surgery
282 Washington Street Hartford, CT 06106
USA


Marisa J. Pacella
Department of Pediatrics
University of Florida
Gainesville, FL
USA


Martha Douglas-Escobar
Department of Pediatrics
University of California San Francisco
CA
USA


Michael D. Weiss
Department of Pediatrics
University of Florida
Gainesville, FL
USA
/
McKnight Brain Institute
University of Florida
Gainesville
FL, USA


Ryan R. Kelly
Research Services
Ralph H. Johnson Veterans Affairs Medical Center
USA
/
Department of Pathology and Laboratory Medicine
Medical University of South Carolina
Charleston
South Carolina


Sergey P. Medvedev
Federal Research Center Institute of Cytology and Genetics
Siberian Branch, Russian Academy of Sciences
Novosibirsk
Russia
/
Institute of Chemical Biology and Fundamental Medicine
Siberian Branch, Russian Academy of Sciences
Novosibirsk
Russia
/
State Research Institute of Circulation Pathology
Novosibirsk
Russia
/
Novosibirsk State University
Novosibirsk
Russia


Suren M. Zakian
Federal Research Center Institute of Cytology and Genetics
Siberian Branch, Russian Academy of Sciences
Novosibirsk
Russia
/
Institute of Chemical Biology and Fundamental Medicine
Siberian Branch, Russian Academy of Sciences
Novosibirsk
Russia
/
State Research Institute of Circulation Pathology
Novosibirsk
Russia
/
Novosibirsk State University
Novosibirsk
Russia


Todd Jensen
Connecticut Children’s Medical Center Department of Surgery
282 Washington Street Hartford, CT 06106
USA


Tong Zheng
McKnight Brain Institute
University of Florida
Gainesville
FL, USA


Wael Sayej
Connecticut Children’s Medical Center Department of Surgery
282 Washington Street Hartford, CT 06106
USA




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