This volume of Frontiers in Heart Failure comprehensively covers the gap between clinical management of heart failure and advanced molecular imaging techniques (SPECT, PET, MRI etc.). These techniques provide valuable evidence to cardiologists for the evaluation and follow-up of heart failure patients. It brings forth established research data regarding the pathophysiology, clinical presentations and therapy of heart failure, in a balance between clinical items and molecular imaging modalities. Readers will also find additional chapters on hybrid cardiovascular imaging techniques as well as guidelines on imaging artifacts and radiation protection. This volume is a useful resource for radiologists, cardiologists, cardiac care nurses and medical physicists.