Editor: Atta-ur-Rahman / Khurshid Zaman; Published on: Nov 30th, 2018.
The seventh volume of the series covers topics such as drug delivery, new avenues for treatment of esophageal cancer and the role of nutrigenomics in finding new therapies.
Topics in Anti-Cancer Research covers important advances on both experimental (preclinical) and clinical cancer research in drug development. The book series offers readers an insight into current and future therapeutic approaches for the prevention of different types of cancers, synthesizing new anti-cancer agents, new patented compounds, targets and agents for cancer therapy as well as recent molecular and gene therapy research.
The comprehensive range of themes covered in each volume will be beneficial to clinicians, immunologists, and R&D experts looking for new anti-cancer targets and patents for the treatment of neoplasms, as well as varied approaches for cancer therapy.
The latest volume of the series starts with a review on non-coding RNAs and associated patents. These patents help researchers to identify various cancer biomarkers and oncogenic regulatory mechanisms. 3 chapters cover nanocarrier patents for enhanced drug delivery of chemotherapeutic agents. Nanocarriers allow drug manufacturers to encapsulate chemotherapeutic agents within thin membranes which allows the molecules to reach the targeted cellular location in the body. The specific topics refer to Nanotaxol which is a nanotechnology enhanced version of Taxol® - a chemotherapeutic agent derived from chemicals in the bark of Taxus brevifolia, stimuli responsive nanocarriers which change behavior according to temperature and pH and smart nanoformulations which rely on different chemical formulations to reach molecular targets. Other topics covered in this volume include the role of autophagy in esophageal cancer, and nutrigenomics (the science of how biological nutrients affect gene expression) in cancer research. In terms of patents, the reader will find a list of compounds which modulate autophagy, and nutrigenomic methods that allow researchers to understand nutritional biomarkers of disease and customize nutraceutical formulations based on genetic and metabolic factors, respectively.
About the Editors:
Atta-ur-Rahman, Ph.D. in organic chemistry from Cambridge University (1968), has over 1080 international publications in several fields of organic chemistry including 751 research publications, 37 international patents, 69 chapters in books and 223 books published largely by major U.S. and European presses. He is the Editor-in-Chief of eight European Chemistry journals. He is Editor of the world's leading encyclopedic series of volumes on natural products, Studies in Natural Product Chemistry, 54 volumes of which have been published under his Editorship by Elsevier during the last two decades.
Dr. Khurshid Zaman is M.Phil. in Molecular Biology, Biochemistry and Biological Sciences from Quaid-e Azam University, Islamabad, Pakistan. She has qualified Ph.D. in Organic Chemistry from H.E.J. Institute of Chemistry, Karachi, Pakistan. Some research work on Trace Element Analysis and Liver regeneration was carried out from Lund University Sweden during her Ph.D. She has done Post Doc. Research from Hamdard University in collaboration with H.E.J. Institute of Chemistry, Karachi, Pakistan and from Geneva, Switzerland in Tissue culture. She has published research papers, reviewers and edited a Book and eBooks. She was the Editor of Pakistan Journal of Scientific Research. She worked in Abbott Laboratories and PCSIR. Serving as a Director Patent, EiC and Executive Editor of Patent Journals at Bentham Science Publishers. Also, Editor of eBook Patent Series on Topics on Anti-Cancer Research. She is also a member of WAME and UNIDO Assessor in Laboratory Accreditation ISO/IEC 17025
Keywords: Cancer, cancer therapy, chemotherapy, non-coding RNAs, drug delivery, nanocarriers, autophagy, esophageal cancer, nutrigenomics, anti-cancer patents