Why Does Vitamin D Matter?

Book Series: Vitamin D and Your Body

Volume 1

by

J. Ruth Wu-Wong

DOI: 10.2174/97816080508331120101
eISBN: 978-1-60805-083-3, 2012
ISBN: 978-1-60805-511-1
ISSN: 2589-3041 (Print)
ISSN: 1879-4475 (Online)



Indexed in: Scopus, Book Citation Index, Science Edition, BIOSIS Previews, Chemical Abstracts, EBSCO.

New tests and studies continue to reveal exciting information about the power of vitamin D in maintaining good health and preventing m...[view complete introduction]
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Does Vitamin D Supplementation Improve Health?

- Pp. 41-56 (16)

Alan H. Lau and Yee Ming Lee

Abstract

There has been a recent plethora of studies uncovering the newly discovered physiological and pharmacological effects of vitamin D. With an increasing recognition of hypovitaminosis D worldwide, there is much interest to address the clinical significance of vitamin D deficiency and identify the most optimal regimen to replenish the body stores through supplementation. With our growing understanding of the non-mineral/bone activities of vitamin D, such as its effects on immune system, cancer and cardiovascular disease, there is a need to establish the optimal means of assessing vitamin D sufficiency and deficiency, the amount of vitamin D needed for optimal body function and how much vitamin D supplementation is required among individuals. As vitamin D is a pre-hormone that can both be synthesized in the body and obtained from the diet, there are challenges in deriving a recommendation. In addition, the amount of vitamin D present in the body is also influenced by factors such as aging, skin pigmentation, concomitant interacting medications and renal disease. For now, 25(OH)D is commonly used to determine vitamin D body stores in studies and clinical practice. This chapter seeks to discuss the issues surrounding vitamin D supplementation in the light of these new findings and address the concern over the vitamin D deficiency with the view that “more vitamin D is not necessarily better”.

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