Medicinal Chemistry - Fusion of Traditional and Western Medicine, First Edition


Robert E. Smith

DOI: 10.2174/97816080514961130101
eISBN: 978-1-60805-149-6, 2013
ISBN: 978-1-60805-154-0

Indexed in: Scopus, EBSCO.

Medicinal Chemistry - Fusion of Traditional and Western Medicine is a textbook ...[view complete introduction]
US $
Buy Personal eBook
Order Library eBook
Order Printed Copy
Order PDF + Printed Copy (Special Offer)

*(Excluding Mailing and Handling)

đź”’Secure Checkout Personal information is secured with SSL technology
Download Flyer

Personalized Medicine and Targeted Drug Delivery

- Pp. 336-349 (14)

Robert E. Smith


Personalized medicine is designed for the specific genetic, epigenetics and environmental properties of the individual and their diseased cells. Eventually, new technologies will enable people to take a drop of blood from their fingertips, analyze it at home and send it to a central computer. The data will be analyzed and compared to the individual’s genome and epigenome. It may also be able to predict whether a patient will respond well to a medicine. People with different genotypes and phenotypes can metabolize drugs differently. The HIV viral genome is always changing, and resistance testing can help doctors choose the drug that will best match the virus and suppress it. The development of new biomarkers through advanced genomic, proteomic, metabolomic and imaging technologies has a very high priority because they can improve diagnosis, and define disease subsets. Clinical trials are being modernized by automating the trials and managing the data. Instead of just making the medicine specific for the DNA that a person is born with, it can also be made specific for a type of cancer. This is being done by developing monoclonal antibodies, which will bind to receptors that are specific for a particular type of cancer. Some of them are even parts of FDA-approved medications. Most can’t kill cells by themselves, but they can still bind to cancer-specific antigens and deliver drugs that are covalently attached to the monoclonal antibody. Thus, there is much research required to bind drugs to monoclonal antibodies, so that the drug only reaches the target organ.

Purchase Chapter  Book Details


Webmaster Contact: Copyright © 2018 Bentham Science