Chemoinformatics: Directions Toward Combating Neglected Diseases


Teodorico C. Ramalho

DOI: 10.2174/97816080518301120101
eISBN: 978-1-60805-183-0, 2012
ISBN: 978-1-60805-502-9

Indexed in: Scopus, EBSCO.

Low-income populations in developing regions of Africa, Asia and the Americas have been particularly injured by a group of tropical in...[view complete introduction]
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Multivariate Image Analysis Applied to QSAR as a Tool for Mosquitoes Control: Dengue and Yellow Fever

- Pp. 154-161 (8)

Matheus P. Freitas, Teodorico C. Ramalho, Elaine F. F. da Cunha and Rodrigo A. Cormanich


An image-based QSAR approach, called Multivariate Image Analysis Applied to Quantitative Structure-Activity Relationships (MIA-QSAR) is described as a tool to model the toxicities of a series of organotin compounds against Aedes aegypti and Anopheles stephensi mosquito larvae, vectors of dengue and yellow fever. This methodology may help researchers to discover novel, potent mosquito controllers.

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