Contribution of Biocatalysis to the Synthesis of β-(1,3)-Glucans
- Pp. 102-111 (10)Vincent Ferrières, Laurent Legentil, Balla Sylla, Karine Descroix, Caroline Nugier-Chauvin and Richard Daniellou
The lightning progress in the understanding of enzymatic mechanisms, democratization of molecular biology tools and their introduction in chemistry laboratories, the pressure of green chemistry notions leading to the need for alternative sustainable and more environmentally friendly approaches, and probably economic factors as well, all these parameters allowed the development of new synthetic strategies based on biocatalysis. This chapter is dedicated to the use of glucosyl hydrolases and some of their mutants, i.e., glucosynthases and thioligases, to the preparation of β-(1,3)-(thio)glucosides.