Synthesis and Biological Applications of Glycoconjugates

by

Olivier Renaudet, Nicolas Spinelli

DOI: 10.2174/97816080527761110101
eISBN: 978-1-60805-277-6, 2011
ISBN: 978-1-60805-537-1



Indexed in: Chemical Abstracts, Scopus, EBSCO.

The interactions between carbohydrates and proteins have been extensively explored in a wide range of physiological and pathological p...[view complete introduction]
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Cyclopeptide-Based Glycoclusters

- Pp. 129-144 (16)

Olivier Renaudet, Didier Boturyn and Pascal Dumy

Abstract

<p>The emergence of glycomics has deeply stimulated the design of new bioactive glycoclusters over the past decade. Among the increasing number of multivalent synthetic structures reported so far, cyclopeptide-based glycoclusters (CBGs) have recently shown promising interest for diverse biological applications. This chapter aims at describing the major advances in this field, with a special focus on the inhibition of carbohydrate-protein interactions and the synthetic vaccines.</p>

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