Synthesis and Biological Applications of Glycoconjugates

by

Olivier Renaudet, Nicolas Spinelli

DOI: 10.2174/97816080527761110101
eISBN: 978-1-60805-277-6, 2011
ISBN: 978-1-60805-537-1



Indexed in: Chemical Abstracts, Scopus, EBSCO.

The interactions between carbohydrates and proteins have been extensively explored in a wide range of physiological and pathological p...[view complete introduction]
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Diels-Alder Based Synthesis of Glycomimetics

- Pp. 240-254 (15)

Cristina Nativi, Elisa Dragoni, Barbara Richichi and Stefano Roelens

Abstract

<p>[4+2] Cycloadditions between “in situ” generated α,α-dioxothiones and unprotected or variously protected glycals provide a powerful synthetic way to obtain glycomimetics chemo-, regio- and stereoselectively. Examples of glycopeptidomimetics and mimetic of tumor antigens are reported.</p>

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