Inositol & its Phosphates: Basic Science to Practical Applications

by

A.K.M. Shamsuddin, Guang-Yu Yang

eISBN: 978-1-68108-007-9, 2015
ISBN: 978-1-68108-008-6



Indexed in: EBSCO.

Inositol and its phosphates are ubiquitous across most life forms, wherein they play important roles in cellular integrity and functio...[view complete introduction]
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Disorders of Metabolism

- Pp. 128-138 (11)

A.K.M. Shamsuddin and Guang-Yu Yang

Abstract

InsP<sub>6</sub> and inositol independently may help in diabetes; InsP<sub>6</sub> by stimulating insulin secretion by the pancreatic β cells. Both inositol and InsP<sub>6</sub> can prevent oxidative damages to the cells and tissues inflicted through advanced glycosylated end products by acting as antioxidants. InsP<sub>6</sub> and inositol could replenish the low intracellular inositol since they do not need insulin to gain entry into the cell. They also have positive effect on the abnormalities of fat metabolism such as hypercholesterolemia and fatty liver.

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