Common Pathogenic Mechanisms between Down Syndrome and Alzheimer's Disease: Steps toward Therapy

Book Series: Recent Advances in Alzheimer Research

Volume 1


Ahmad Salehi, Michael Rafii, Cristy Phillips

DOI: 10.2174/97816810813801150101
eISBN: 978-1-68108-138-0, 2015
ISBN: 978-1-68108-139-7
ISSN: 2452-2554 (Print)
ISSN: 2452-2562 (Online)

Indexed in: Scopus, EBSCO.

Down syndrome is a chromosomal disorder affecting more than 5.8 million individuals worldwide. Down syndrome can be viewed as a comple...[view complete introduction]
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The Management and Treatment of Down Syndrome and Alzheimer’s Disease: Political and Ethical Issues

- Pp. 3-19 (17)

Betsy Pohlman


This chapter explores the entangled histories of Down syndrome and Alzheimer’s disease, advocacy endeavors, parental experimentation with cognitive therapies, and uneasy relationships between parents, medicine, and science. The goal is to raise questions to elicit discussion for parent advocates, who may find themselves at the crossroads of new possibilities for people with Down syndrome. It is drawn from anthropological ethnographic research centered on social advocacy for both Down syndrome and Alzheimer’s disease, conducted from 2006-2010. The author also utilizes historical analysis to enhance understanding of contemporary concerns, and to illuminate the unique position of parents in the treatment of their young and adult children with Down syndrome.

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