Chapter 6

Mechanotransduction in Chondrocytes

Marwan Haddad, Jacob Shapira and Nahum Rosenberg

Abstract

Mechanical load is the cardinal factor in regulating the metabolic activity of chondrocytes. Chondrocytes are sensitive to load pattern and can adjust their metabolism according to the magnitude and frequency of mechanical stress. Quantity and quality characterization of the chondrocyte response to stress is yet to be revealed and may lead to novel therapeutic methods in preventing and treatment of cartilage degeneration diseases.

Total Pages: 59-64 (6)

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