Polarity index in Proteins-A Bioinformatics Tool

by

Carlos Polanco

DOI: 10.2174/97816810826911160101
eISBN: 978-1-68108-269-1, 2016
ISBN: 978-1-68108-270-7



Indexed in: Book Citation Index, Science (BKCI-S), BIOSIS Previews, EBSCO.

Polarity is a physico-chemical property that characterizes the electromagnetic stability of a protein and can be used to predict its p...[view complete introduction]
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Pathogenic Bacteria

- Pp. 36-49 (14)

Carlos Polanco

Abstract

This chapter includes the identification of a group of peptides known as antimicrobial peptides. They have an important role in the immune system of all living organisms. The identification of the main function associated to each peptide was made by calculating the polar profile of the peptide with the QSAR method called polarity index, already described in Sect. 3.3. The peptides computationally tested were taken from two different databases: Antimicrobial Peptides Database (APD2), and Uniprot Database, which included the set of peptides called selective cationic amphipatic antibacterial peptides.

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