Frontiers in Clinical Drug Research- HIV

Volume 4

by

Atta-ur-Rahman, FRS

DOI: 10.2174/97816810852651170401
eISBN: 978-1-68108-526-5, 2018
ISBN: 978-1-68108-527-2
ISSN: 2468-0397 (Print)
ISSN: 2352-5916 (Online)



Indexed in: Scopus.

Frontiers in Clinical Drug Research – HIV is a book series that brings updated reviews to readers interested in learn...[view complete introduction]
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Potential Magnetic Nanotherapeutics for Management of neuroAIDS

- Pp. 34-60 (27)

Vidya Sagar, Arti Vashist and Madhavan Nair

Abstract

The human immunodeficiency virus (HIV) infection into the brain induces neurotoxicity and neuropathology which are collectively termed as the neuroAIDS. Brain delivery of therapeutic molecules continues to be the greatest challenge, primarily because of the tightly-junctioned blood-brain barrier (BBB). Several nanovehicles are under intensive examination for delivering drugs across the BBB. Magnetic nanoparticles (MNPs) possess advantages over their counterparts because of their potential utilization for non-invasive brain targeting using external magnetic force. MNPs can be physicochemically modulated for engineering smart drug delivery carrier as well. Nonetheless, rigorous research is required to fix associated shortcomings of MNPs before their real-time application.

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