Science of Spices and Culinary Herbs - Latest Laboratory, Pre-clinical, and Clinical Studies

Volume 1

by

Atta-ur-Rahman , Muhammad Iqbal Choudhary , Sammer Yousuf

DOI: 10.2174/97816810875111190101
eISBN: 978-1-68108-751-1, 2019
ISBN: 978-1-68108-752-8
ISSN: 2590-0773 (Print)
ISSN: 2590-0781 (Online)



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Many herbs and spices, in addition to their culinary use for taste, contain chemical compounds which have medicinal uses. For...[view complete introduction]
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Table of Contents

Preface

- Pp. i-ii (2)
Atta-ur-Rahman, M. Iqbal Choudhary and Sammer Yousuf
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List of Contributors

- Pp. iii-iv (2)
Atta-ur-Rahman, M. Iqbal Choudhary and Sammer Yousuf
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Saffron: The Golden Spice

- Pp. 1-29 (29)
Maryam Akaberi, Zahra Boghrati, Mohammad Sadegh Amiri and Seyed Ahmad Emami

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The Effect of Crocus Sativus (Saffron) on the Respiratory System: Traditional and Experimental Evidence

- Pp. 30-54 (25)
Mohammad Hossein Boskabady, Zahra Gholamnezhad, Vahideh Ghorani and Saeideh Saadat

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Nutraceutical Activities of Turmeric (Curcuma longa) and its Bioactive Constituent Curcumin

- Pp. 55-73 (19)
Krishnapura Srinivasan

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Antibacterial and Anticancer Activities of Turmeric and its Active Ingredient Curcumin, and Mechanism of Action

- Pp. 74-103 (30)
Dev Bukhsh Singh, Ajay Kumar Maurya and Dipti Rai

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Strategies for Enhancement of Bioavailability and Bioactivity of Curcumin

- Pp. 104-147 (44)
D. Nedra Karunaratne, Geethi K. Pamunuwa, Irosha H. V. Nicholas and Isuru R. Ariyarathna

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Effect of Curcumin on the Diversity of Gut Microbiota

- Pp. 148-174 (27)
Wissam Zam

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Turmeric and Inflammatory Diseases: An Overview of Clinical Evidence

- Pp. 175-197 (23)
Roodabeh Bahramsoltani, Samaneh Soleymani, Roja Rahimi and Mohammad Hosein Farzaei

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Pre-Clinical/Animal Studies Conducted on Turmeric and Curcumin and Their Formulations

- Pp. 198-225 (28)
Rupesh K. Gautam, Disha Arora and Swapnil Goyal

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Subject Index

- Pp. 226-235 (10)
Atta-ur-Rahman, M. Iqbal Choudhary and Sammer Yousuf
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Preface

Herbs and spices have been used by humans since centuries. Apart from their culinary, recreational, and aromatic values, many of them have been used for medicinal purposes. Spice trades have played an important role in the spread of religions, political influences and colonization. Culinary herbs and spices are integral part of various traditional systems of medicine and cultural practices, including ancient Egyptian, Chinese, Ayurveda, and Greeco-Arab systems. Many of them are used in indigenous medicines and home remedies.

Ethnobotanic uses of spices, including anti-inflammatory, anti-diabetic, promoters of cardiovascular health, anti-aging, pain relieving, and aphrodisiac are very well known. More recently, a lot of scientific work has been conducted to validate the ethnobotanic uses of spices, as well as to identify their new uses. Mechanism of actions of many secondary metabolites, obtained from spices and culinary herbs, have also been deciphered in the recent scientific literature. With the growing interest in natural products, spices have received major scientific and commercial interest. Their dietary origin and safety profile make them especially attractive for therapeutic and nutraceutical development. Global interest in spices in health and economy are thus driving huge scientific R&D all over the world.

The book series entitled, “Science of Spices and Culinary Herbs - Latest Laboratory, Pre-Clinical, and Clinical Studies is an attempt to provide the much needed comprehensive literature reviews and critical analysis of extensive research work currently being conducted on common spices, and herbs. Carefully chosen articles in the first volume of the book series are focused on two globally common spices, saffron and turmeric, and their key constituents. Eight scholarly written articles by leading experts, encompass key research and development studies on these two spices, including ethnobotanic uses, and pre-clinical and clinical studies.

Emami et al., have contributed a comprehensive review on ethnobotanic and scientific studies on saffron (Crocus sativus L.) and its constituents. The chapter written by Boskabady et al., focuses on the effect of saffron on respiratory diseases, along with phytochemistry and clinical evidence.

Turmeric has long been used for anti-inflammatory effects in various traditional systems of medicine. Krishnapura Srinivasan has written an excellent review of nutraceutical and therapeutic properties of turmeric (Curcuma longa L.). On the same theme, Singh et al., have focused on the recent work on anti-bacterial and anti-cancer properties of turmeric and its most important constituent, curcumin, one of the most studied natural products. Karunaratne et al., have contributed a chapter on various strategies for enhancement of bioavailability and bioactivity of curcumin in pre-clinical and clinical trials. The review by Wissam Zam is focused on the effect of curcumin on the diversity of gut microbiota, and related diseases. Farzaei et al., have written a comprehensive review on the clinical studies on turmeric and its key constituent curcumin in anti-inflammatory diseases. Last but not least, Goyal et al., have provided an excellent overview of pre-clinical and clinical studies on turmeric and curcumin, with reference to a broad range of diseases.

The above-cited reviews cover over 960 references for scientific studies on these two key spices. This illustrates the overwhelming scientific and general interest in the field and firmly establishes the need for a book series which provides state-of-the-art reviews to the readers.

We are most grateful to all contributors for their excellent reviews and critical analysis of the recent literature, and for timely submissions of their chapters. We would like to express our gratitude to the excellent coordination of Ms. Fariya Zulfiqar (Manager Publications), Mr. Mahmood Alam (Director Publications), and the entire production team of Bentham Science Publishers for the timely completion and release of the first volume of this important book series. We sincerely hope that this new book series on the most important dietary and medicinal natural products will contribute to a better understanding of the subject and contribute towards further research and development in this field.

Prof. Dr. Atta-ur-Rahman, FRS
Kings College
University of Cambridge
Cambridge
UK

Prof. Dr. M. Iqbal Choudhary
&
Dr. Sammer Yousuf
H.E.J. Research Institute of Chemistry
International Center for Chemical and Biological Sciences
University of Karachi
Karachi
Pakistan

List of Contributors

Editor(s):
Prof. Atta-ur-Rahman FRS
University of Cambridge
Kings College
Cambridge
UK


Prof. Muhammad Iqbal Choudhary
University of Karachi
H.E.J. Research Institute of Chemistry
Karachi
Pakistan


Sammer Yousuf
University of Karachi
H.E.J. Research Institute of Chemistry
Karachi
Pakistan




Contributor(s):
Ajay Kumar Maurya
Department of Food Technology, Institute of Biosciences and Biotechnology
Chhatrapati Shahu Ji Maharaj University
Kanpur-208024
India


Dipti Rai
Department of Food Technology, Institute of Biosciences and Biotechnology
Chhatrapati Shahu Ji Maharaj University
Kanpur-208024
India


D. Nedra Karunaratne
Department of Chemistry
University of Peradeniya
Peradeniya
Sri Lanka


Dev Bukhsh Singh
Department of Biotechnology
Institute of Biosciences and Biotechnology, Chhatrapati Shahu Ji Maharaj University
Kanpur-208024
India


Disha Arora
Department of Pharmacognosy, MM School of Pharmacy
Maharishi Markandeshwar University
Sadopur-Ambala-134007
India


Geethi K. Pamunuwa
Department of Horticulture and Landscape Gardening, Faculty of Agriculture and Plantation Management
Wayamba University of Sri Lanka
Makandura
Sri Lanka


Irosha H. V. Nicholas
Department of Biochemistry, Faculty of Medicine
Sabaragamuwa University of Sri Lanka
Ratnapura
Sri Lanka


Isuru R. Ariyarathna
Department of Chemistry and Biochemistry
Auburn University
Auburn, AL, 36849
USA


Krishnapura Srinivasan
Department of Biochemistry
CSIR – Central Food Technological Research Institute
Mysore - 570020
India


Maryam Akaberi
Department of Pharmacognosy, School of Pharmacy
Mashhad University of Medical Sciences
Mashhad
Iran


Mohammad Hosein Farzaei
Pharmaceutical Sciences Research Center
Health Institute, Kermanshah University of Medical Sciences
Kermanshah
Iran
/
Medical Biology Research Center
Kermanshah University of Medical Sciences
Kermanshah
Iran


Mohammad Hossein Boskabady
Neurogenic Inflammation Research Center
Mashhad University of Medical Sciences
Mashhad
Iran
/
Department of Physiology, Faculty of Medicine
Mashhad University of Medical Sciences
Mashhad
Iran


Mohammad Sadegh Amiri
Department of Biology
Payame Noor University
Tehran
Iran


Roodabeh Bahramsoltani
Department of Traditional Pharmacy, School of Persian Medicine
Tehran University of Medical Sciences
Tehran
Iran
/
PhytoPharmacology Interest Group (PPIG)
Universal Scientific Education and Research Network (USERN)
Tehran
Iran


Roja Rahimi
Department of Traditional Pharmacy, School of Persian Medicine
Tehran University of Medical Sciences
Tehran
Iran
/
PhytoPharmacology Interest Group (PPIG)
Universal Scientific Education and Research Network (USERN)
Tehran
Iran


Rupesh K. Gautam
Department of Pharmacology, MM School of Pharmacy
Maharishi Markandeshwar University
Sadopur-Ambala-134007
India


Saeideh Saadat
Neurogenic Inflammation Research Center
Mashhad University of Medical Sciences
Mashhad
Iran
/
Department of Physiology, Faculty of Medicine
Mashhad University of Medical Sciences
Mashhad
Iran


Samaneh Soleymani
Department of Traditional Pharmacy, School of Persian Medicine
Tehran University of Medical Sciences
Tehran
Iran
/
PhytoPharmacology Interest Group (PPIG)
Universal Scientific Education and Research Network (USERN)
Tehran
Iran


Seyed Ahmad Emami
Department of Pharmacognosy, School of Pharmacy
Mashhad University of Medical Sciences
Mashhad
Iran
/
Department of Traditional Medicine, School of Pharmacy
Mashhad University of Medical Sciences
Mashhad
Iran


Swapnil Goyal
B. R. Nahata College of Pharmacy
Mandsaur University
Mandsaur (M.P.)-458001
India


Wissam Zam
Department of Analytical and Food Chemistry, Faculty of Pharmacy
Al-Andalus University for Medical Sciences
Tartous
Syrian Arab Republic


Vahideh Ghorani
Neurogenic Inflammation Research Center
Mashhad University of Medical Sciences
Mashhad
Iran
/
Department of Physiology, Faculty of Medicine
Mashhad University of Medical Sciences
Mashhad
Iran


Zahra Gholamnezhad
Neurogenic Inflammation Research Center
Mashhad University of Medical Sciences
Mashhad
Iran
/
Department of Physiology, Faculty of Medicine
Mashhad University of Medical Sciences
Mashhad
Iran


Zahra Boghrati
Department of Traditional Medicine, School of Pharmacy
Mashhad University of Medical Sciences
Mashhad
Iran




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