Frontiers in Clinical Drug Research - Alzheimer Disorders

Volume 8

by

Atta-ur-Rahman

DOI: 10.2174/97898114018931190801
eISBN: 978-981-14-0189-3, 2019
ISBN: 978-981-14-0190-9
ISSN: 2451-8743 (Print)
ISSN: 2214-5168 (Online)



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Table of Contents

Preface

- Pp. i
Atta-ur-Rahman
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List of Contributors

- Pp. ii-iii (2)
Atta-ur-Rahman
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Novel Molecular Targets of Tauopathy; Therapeutic and Diagnostic Applications

- Pp. 1-32 (32)
Yasmeen M. Taalab, Mohamed El-Gamal and Mohamed Salama
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The Therapy of Alzheimer’s Disease: Towards a New Generation of Drugs

- Pp. 33-80 (48)
Luca Piemontese, Fulvio Loiodice, Sílvia Chaves and Maria Amelia Santos
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Could Antibiotics Be Therapeutic Agents in Alzheimer’s Disease?

- Pp. 81-128 (48)
Oscar Gomez-Torres, Cristina Pintado-Losa, Maria Rodriguez-Perez and Emma Burgos-Ramos
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Use of Antipsychotics in Patients with Alzheimer’s Disease

- Pp. 129-153 (25)
Haiyun Xu, Jue He, Xiaoyin Zhuang and Yuan Shao
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Approaches Based on Cholinergic Hypothesis and Cholinesterase Inhibitors in the Treatment of Alzheimer's Disease

- Pp. 154-190 (37)
Zeynep Ozdemir, Azime-Berna Ozcelik and Mehtap Uysal
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Potential Biological Mechanisms with Prophylactic Action in Rapid Cognitive Impairment in Late- Onset Alzheimer's Disease

- Pp. 191-261 (71)
Ileana Marinescu, Puiu Olivian Stovicek, Dragos Marinescu and Laurentiu Mogoanta
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Subject Index

- Pp. 262-270 (9)
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Preface

The book series Frontiers in Clinical Drug Research-Alzheimer Disorders presents important recent developments in the form of cutting edge reviews written by the authorities in the field. The chapters in the 8th volume are focused on different therapeutic agents being employed or under development for treating Alzheimer’s disease.

Salama et al., in Chapter 1 discuss the structure, functions and interactions of tau protein with reference to the potential therapeutic targets for the treatment of tauopathies. Piemontese et al., in Chapter 2 present the new generation of drugs as potential therapy for Alzheimer’s disease. Chapter 3 by Burgos-Ramos et al., reviews the neuroprotective role of some antibiotics as therapeutic means in Alzheimer’s disease.

Chapter 4 by Xu et al., describes the use of antipsychotics in patients with Alzheimer’s disease. ÖZDEMİR et al., in chapter 5, discuss the role of cholinergic hypothesis and cholinesterase inhibitors for the treatment of Alzheimer's disease. The last chapter by Stovicek et al., discusses the potential biological mechanisms with prophylactic action in rapid cognitive impairment in late-onset Alzheimer's disease.

I am grateful to all the eminent scientists for their excellent contributions. The efforts of Ms. Fariya Zulfiqar (Manager Publications) & Mr. Shehzad Naqvi (Editorial Manager Publications) and the leadership of Mr. Mahmood Alam (Director Publications) are greatly appreciated.



Prof. Atta-ur-Rahman, FRS
Kings College,
University of Cambridge,
Cambridge,
UK

List of Contributors

Editor(s):
Atta-ur-Rahman FRS
Kings College, University of Cambridge
Honorary Life Fellow
Cambridge
UK




Contributor(s):
Azime-Berna ÖZÇELİK
Department of Pharmaceutical Chemistry
Gazi University, Faculty of Pharmacy
Ankara
Turkey


Cristina Pintado-Losa
Biochemistry Area
Faculty of Environmental Sciences and Biochemistry, University of Castilla-La Mancha
Toledo
Spain


Dragoș Marinescu
Member of the Romanian Academy of Medical Sciences, University of Medicine and Pharmacy of Craiova, Doctoral School
Interim President of the Romanian Society for Biological Psychiatry and Psychopharmacology
Romania


Emma Burgos-Ramos
Biochemistry Area
Faculty of Environmental Sciences and Biochemistry, University of Castilla-La Mancha
Toledo
Spain


Fulvio Loiodice
Dipartimento di Farmacia–Scienze del Farmaco
Università degli Studi di Bari “Aldo Moro”
Via E. Orabona 4, 70125 Bari
Italy


Haiyun Xu
The Mental Health Center, Shantou University Medical College, Shantou
PR China


Ileana Marinescu
Department of Psychiatry
University of Medicine and Pharmacy of Craiova
Craiova
Romania


Jue He
First Affiliated Hospital, Institute of Neurological Disease, Henan University
Henan
PR China;
/
Xiamen Xian Yue Hospital
Xiamen
Fujian
PR China


Laurențiu Mogoantă
Department of Morphopathology
University of Medicine and Pharmacy of Craiova
Craiova
Romania


Luca Piemontese
Dipartimento di Farmacia–Scienze del Farmaco
Università degli Studi di Bari “Aldo Moro”
Via E. Orabona 4, 70125 Bari
Italy


Maria Amélia Santos
Centro de Química Estrutural
Instituto Superior Técnico, Universidade de Lisboa, Av. Rovisco Pais 1
1049-001 Lisboa
Portugal


María Rodríguez-Pérez
Biochemistry Area
Faculty of Environmental Sciences and Biochemistry, University of Castilla-La Mancha
Toledo
Spain


Mehtap UYSAL
Department of Pharmaceutical Chemistry
Gazi University, Faculty of Pharmacy
Ankara
Turkey


Mohamed El-Gamal
Toxicology Department & Medical Experimental Research Center (MERC)
Faculty of Medicine, Mansoura University
Mansoura
Egypt;
/
IUF – Leibniz Research Institute for Environmental Medicine
Düsseldorf
Germany


Mohamed Salama
Toxicology Department & Medical Experimental Research Center (MERC)
Faculty of Medicine, Mansoura University
Mansoura
Egypt


Oscar Gómez-Torres
Biochemistry Area
Faculty of Environmental Sciences and Biochemistry, University of Castilla-La Mancha
Toledo
Spain


Puiu Olivian Stovicek
Department of Pharmacology
“Titu Maiorescu” University of Bucharest, Faculty of Nursing, Târgu Jiu
Romania



Sílvia Chaves
Centro de Química Estrutural
Instituto Superior Técnico, Universidade de Lisboa, Av. Rovisco Pais 1
1049-001 Lisboa
Portugal


Xiaoyin Zhuang
The Mental Health Center, Shantou University Medical College, Shantou
PR China


Yasmeen M. Taalab
Toxicology Department
Faculty of Medicine, Mansoura University
Mansoura
Mansoura;
/
German Institute of Disaster Medicine and Emergency Medicine
Tubingen
Germany


Yuan Shao
Shenzhen Mental Health Center, Shenzhen Kangning Hospital, Shenzhen Shi
PR China


Zeynep ÖZDEMİR
Department of Pharmaceutical Chemistry
İnönü University, Faculty of Pharmacy
Malatya
Turkey




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