Changing Views on Living Organisms

Book Series: Advances in Genome Science

Volume 1

by

Christian Neri

DOI: 10.2174/97816080512981130101
eISBN: 978-1-60805-129-8, 2013
ISBN: 978-1-60805-134-2
ISSN: 2213-6606

  
  




Genome science or genomics is essential to advancing knowledge in the fields of biology and medicine. Specifically, researchers learn ...[view complete introduction]
PDF US $
- Single user / Non-Library usage: 99
- Multi user / Library usage: 396
Print-On-Demand (P.O.D): *182
Special Offer for Single user / Non-Library usage (PDF + P.O.D): *231

*(Excluding Mailing and Handling)
Purchase: Book Chapters

Table of Contents

Foreword , Pp. i- (1)

Erich Wanker

Download Free

Preface , Pp. ii- (1)

Christian Neri

Download Free

List of Contributors , Pp. iii-ix (7)

Christian Neri

Download Free

Endometrial Cancer as a Familial Tumor: Pathology and Molecular Carcinogenesis , Pp. 3-14 (12)

Kouji Banno, Megumi Yanokura, Kennta Masuda, Arisa Ueki, Iori Kisu, Yusuke Kobayashi, Wataru Yamagami, Nobuyuki Susumu and Daisuke Aoki

View Abstract Purchase Chapter

Replication Origins and Timing of Temporal Replication in Budding Yeast: How to Solve the Conundrum? , Pp. 15-44 (30)

Matteo Barberis, Thomas W. Spiesser and Edda Klipp

View Abstract Purchase Chapter

The Role of Androgen Receptor Mutations in Progression of Prostate Cancer , Pp. 45-65 (21)

G.N. Brooke, J. Waxman and C. L. Bevan

View Abstract Purchase Chapter

MUTYH Associated Polyposis (MAP) , Pp. 66-100 (35)

M.L.M. Binderup and M.L. Bisgaard

View Abstract Download Free

Gene Clusters, Molecular Evolution and Disease: A Speculation , Pp. 101-145 (45)

Alireza Baradaran-Heravi, Leah I. Elizondo and Cornelius F. Boerkoel

View Abstract Purchase Chapter

Expression and Function of Kruppel Like-Factors (KLF) in Carcinogenesis , Pp. 146-168 (23)

Diab Thoria, Bureau Christophe, Hanoun Naima, Torrisani Jérôme, Vinel Jean-Pierre, Buscail Louis and Cordelier Pierre

View Abstract Purchase Chapter

Episcopic 3D Imaging Methods: Tools for Researching Gene Function , Pp. 169-188 (20)

Wolfgang J. Weninger and Stefan H. Geyer

View Abstract Purchase Chapter

Drosophila Lethal Giant Larvae Neoplastic Mutant as a Genetic Tool for Cancer Modelling , Pp. 189-209 (21)

Francesca Froldi, Marcello Ziosi, Annalisa Pession and Daniela Grifoni

View Abstract Purchase Chapter

Genetic Insights Through Genome Wide Association Studies in Type 2 Diabetes Mellitus will Lead to New Therapeutics , Pp. 210-240 (31)

Marcel G. M. Wolfs, Naishi Li, Jingyuan Fu, Cisca Wijmenga, Timon W. van Haeften and Marten H. Hofker

View Abstract Purchase Chapter

Indispensable Roles of Plastids in Arabidopsis thaliana Embryogenesis – Update , Pp. 241-260 (20)

Mehdi Nafati and Kentaro Inoue

View Abstract Purchase Chapter

Mass Spectrometry-Based Approaches Toward Absolute Quantitative Proteomics , Pp. 261-292 (32)

Keiji Kito and Takashi Ito

View Abstract Purchase Chapter

Regulation of Interactions with Sliding Clamps During DNA Replication and Repair , Pp. 293-315 (23)

Francisco J. López de Saro

View Abstract Purchase Chapter

Revealing Gene Function and Genetic Diversity in Plants and Animals via TILLING and EcoTILLING , Pp. 316-351 (36)

N.A. Barkley and M.L. Wang

View Abstract Purchase Chapter

Variations Around the Arrestin Fold , Pp. 352-376 (25)

Laurence Aubry, Dorian Guetta and Gérard Klein

View Abstract Purchase Chapter

Role of Calcium Regulated Kinases: Expressional and Functional Analysis in Abiotic Stress Signaling , Pp. 377-425 (49)

Ritika Das, Amita Pandey and Girdhar K. Pandey

View Abstract Purchase Chapter

Multiple Hsp70 Isoforms in the Eukaryotic Cytosol: Evidence for Both Redundant and Specialized Functions , Pp. 426-451 (26)

Mehdi Kabani and Céline N. Martineau

View Abstract Purchase Chapter

Mitochondrial and Nuclear Genes of Mitochondrial Components in Cancer , Pp. 452-490 (39)

E. Kirches

View Abstract Purchase Chapter

Index , Pp. 491-528 (38)

Christian Neri

Download Free

Foreword

Genome science has become essential in advancing knowledge in the wide field of biological and clinical research. The eBook 'Advances in Genome Science' is intended to provide the community with a multi-disciplinary and accessible view of some of the latest developments in the field, allowing readers to capture the relevance and diversity of genomics.

Emerging in the 1980s with the availability of exiting new techniques that allowed larger systematic studies of more than one gene, gaining speed in the 1990s with the genome projects and today, going through a period of conceptual and technological refinement and differentiation. Genomics is at the brink of yielding the scientific and medical progress the public and the research communities in basic, applied and clinical science have been hoping for and expecting.

The challenges that still lie ahead are great and the best use of the possibilities of genomics will be necessary to tackle them and provide solutions to urgent medical and environmental problems. While the substantial investment in large scale genomics studies has repeatedly been discussed in critical terms, genomics researchers as a result can now focus on the evaluation of the valuable, comprehensive datasets that have been generated. Theoretical approaches have started to yield testable models of biological processes, hypothesis-driven investigation into disease mechanisms or signaling pathways has been provided with exiting new leads, identification of new therapy targets has a broader, more detailed knowledge base to start from.

‘Advances in Genome Science’ allows a look at the cutting-edge genomics approaches in use today that bridge the gap to translational science and personalized medicine and are certain to change the way we think about genetic information even more.

Erich Wanker
PI Neuroproteomics and Molecular Mechanisms of Neurodegeneration at
Max Delbrück Center for Molecular Medicine, Berlin-Buch
Full Professor of Molecular Medicine at Charité University Medicine Berlin
Germany


Preface

'Genome science has contributed to understanding how biological processes may develop in living organisms on a global-scale level, resulting in significant progresses in various fields such as molecular evolution, development, plant genetics, aging and disease research. This eBook brings together reviews from different aspects of genome science research and selected topics provide an updated introduction to the diversity of impact in the field. The eBook is a valuable reference and handbook for researchers and clinicians, as well as students and medical professionals interested in the impact of genome science on our understanding of normal and pathological biological processes.'

Christian Neri
ABC

List of Contributors

Editor(s):
Christian Neri
Research Director at INSERM, Laboratory of Neuronal Cell Biology & Pathology
Psychiatry and Neuroscience Center U894
2 ter rue d'Alesia
Paris, 75014
France




Contributor(s):
Kouji Banno
Department of Obstetrics and Gynecology
Keio University School of Medicine
Tokyo
Japan


Megumi Yanokura
Department of Obstetrics and Gynecology
Keio University School of Medicine
Tokyo
Japan


Kennta Masuda
Department of Obstetrics and Gynecology
Keio University School of Medicine
Tokyo
Japan


Arisa Ueki
Department of Obstetrics and Gynecology
Keio University School of Medicine
Tokyo
Japan


Iori Kisu
Department of Obstetrics and Gynecology
Keio University School of Medicine
Tokyo
Japan


Yusuke Kobayashi
Department of Obstetrics and Gynecology
Keio University School of Medicine
Tokyo
Japan


Wataru Yamagami
Department of Obstetrics and Gynecology
Keio University School of Medicine
Tokyo
Japan


Nobuyuki Susumu
Department of Obstetrics and Gynecology
Keio University School of Medicine
Tokyo
Japan


Daisuke Aoki
Department of Obstetrics and Gynecology
Keio University School of Medicine
Tokyo
Japan


Matteo Barberis
Institute for Biology, Theoretical Biophysics, Humboldt University Berlin
Invalidenstraβe 42
Berlin, 10115
Germany


Thomas W. Spiesser
Institute for Biology, Theoretical Biophysics, Humboldt University Berlin
Invalidenstraβe 42
Berlin, 10115
Germany


Edda Klipp
Institute for Biology, Theoretical Biophysics, Humboldt University Berlin
Invalidenstraβe 42
Berlin, 10115
Germany


Greg N. Brooke
Department of Surgery and Cancer
Androgen Signalling Laboratory, Imperial College London
London W12 0NN
UK


Jonathan Waxman
Department of Surgery and Cancer
Androgen Signalling Laboratory, Imperial College London
London W12 0NN
UK


Charlotte. L. Bevan
Department of Surgery and Cancer
Androgen Signalling Laboratory, Imperial College London
London W12 0NN
UK


Marie Louise M. Binderup
Department of Cellular and Molecular Medicine
University of Copenhagen, Panum Institute
24.4, Blegdamsvej 3, 2200 Copenhagen N
Denmark


Marie L. Bisgaard
Department of Cellular and Molecular Medicine
University of Copenhagen, Panum Institute
24.4, Blegdamsvej 3, 2200 Copenhagen N
Denmark


Alireza Baradaran-Heravi
Department of Medical Genetics
Child and Family Research Institute, University of British Columbia, Vancouver
British Columbia
Canada


Leah I. Elizondo
Department of Medical Genetics, University of British Columbia
Centre for Molecular Medicine and Therapeutics, Child and Family Research Institute
Vancouver
Canada


Cornelius F. Boerkoel
Department of Medical Genetics
Child and Family Research Institute, University of British Columbia, Vancouver
British Columbia
Canada


Diab Thoria
INSERM U1037
CRCT Team 10, 1, avenue Jean Poulhes, BP 84225, 31432 04
Toulouse Cedex
France


Bureau Christophe
INSERM U1037
CRCT Team 10, 1, avenue Jean Poulhes, BP 84225, 31432 04
Toulouse Cedex
France


Hanoun Naima
INSERM U1037
CRCT Team 10, 1, avenue Jean Poulhes, BP 84225, 31432 04
Toulouse Cedex
France


Torrisani Jérôme
INSERM U1037
CRCT Team 10, 1, avenue Jean Poulhes, BP 84225, 31432 04
Toulouse Cedex
France


Vinel Jean-Pierre
INSERM U1037
CRCT Team 10, 1, avenue Jean Poulhes, BP 84225, 31432 04
Toulouse Cedex
France


Buscail Louis
INSERM U1037
CRCT Team 10, 1, avenue Jean Poulhes, BP 84225, 31432 04
Toulouse Cedex
France


Cordelier Pierre
INSERM U1037
CRCT Team 10, 1, avenue Jean Poulhes, BP 84225, 31432 04
Toulouse Cedex
France


Wolfgang J. Weninger
IMG, Centre for Anatomy and Cell Biology, Medical University of Vienna
Waehringer Str. 13
Vienna, A-1090
Austria


Stefan H. Geyer
IMG, Centre for Anatomy and Cell Biology, Medical University of Vienna
Waehringer Str. 13
Vienna, A-1090
Austria


Francesca Froldi
Departments of Biologia Evoluzionistica Sperimentale, and Patologia Sperimentale
Cancer Modelling in Drosophila, Alma Mater Studiorum
Bologna
Italy


Marcello Ziosi
Departments of Biologia Evoluzionistica Sperimentale, and Patologia Sperimentale
Cancer Modelling in Drosophila, Alma Mater Studiorum
Bologna
Italy


Annalisa Pession
Departments of Biologia Evoluzionistica Sperimentale, and Patologia Sperimentale
Cancer Modelling in Drosophila, Alma Mater Studiorum
Bologna
Italy


Daniela Grifoni
Departments of Biologia Evoluzionistica Sperimentale, and Patologia Sperimentale
Cancer Modelling in Drosophila, Alma Mater Studiorum
Bologna
Italy


Marcel G. M. Wolfs
Department of Pathology and Medical Biology, Medical Biology Section, Molecular Genetics
University Medical Center Groningen
University of Groningen, Hanzeplein 1
Groningen, 9713 GZ
the Netherlands


Naishi Li
Department of Endocrinology, Key Laboratory of Endocrinology of Ministry of Health
Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Science
Beijing, 100730
China


Jingyuan Fu
Department of Genetics
University Medical Center Groningen, University of Groningen
PO Box 30001, 9700 RB
Groningen
the Netherlands


Cisca Wijmenga
Department of Genetics
University Medical Center Groningen, University of Groningen
PO Box 30001, 9700 RB
Groningen
the Netherlands


Timon W. van Haeften
Department of Internal Medicine
G 02-228, University Medical Center Utrecht
PO Box 85500
Utrecht
GA, 3508
the Netherlands


Marten H. Hofker
Department of Pathology and Medical Biology
Medical Biology Section, Molecular Genetics, University Medical Center Groningen, University of Groningen
Hanzeplein 1
Groningen
GZ, 9713
the Netherlands


Mehdi Nafati
Department of Plant Sciences
University of California
Davis
CA, 95616
USA


Kentaro Inoue
Department of Plant Sciences
University of California
Davis
CA, 95616
USA


Keiji Kito
Department of Life Science
School of Agriculture, Meiji University
Kawasaki, 214-8571
Japan


Takashi Ito
Department of Biophysics and Biochemistry
Graduate School of Science, University of Tokyo
Tokyo, 113-0032
Japan


Francisco J. López de Saro
Department of Molecular Evolution
Centro de Astrobiología (CSIC-INTA), Torrejón de Ardoz
Madrid, 28850
Spain


Noelle A. Barkley
USDA-ARS
Plant Genetic Resources Conservation Unit (PGRCU)
1109 Experiment Street
Griffin
GA, 30223
USA


Ming L. Wang
USDA-ARS
Plant Genetic Resources Conservation Unit (PGRCU)
1109 Experiment Street
Griffin
GA, 30223
USA


Laurence Aubry
CEA, DSV, iRTSV
Laboratoire Biologie à Grande Echelle
Grenoble, F-38054
France


Dorian Guetta
INSERM, U1038
Grenoble, F-38054
France


Gérard Klein
BGE/OdyCell, Institut de Recherches en Technologies et Sciences pour le Vivant
CEA-Grenoble, 17 avenue des Martyrs
Grenoble Cedex 9, 38054
France


Ritika Das
Department of Biology
University of Rochester, Rochester
New York, 14627
USA


Amita Pandey
Department of Plant Molecular Biology
University of Delhi South Campus
New Delhi, 110021
India


Girdhar K. Pandey
Department of Plant Molecular Biology
University of Delhi South Campus
New Delhi, 110021
India


Mehdi Kabani
Laboratoire d’Enzymologie et Biochimie Structurales (LEBS)
CNRS, Bât. 34, Avenue de la Terrasse
Gif-sur-Yvette, 91198
France


Céline N. Martineau
Laboratoire d’Enzymologie et Biochimie Structurales (LEBS)
CNRS, Bât. 34, Avenue de la Terrasse
Gif-sur-Yvette, 91198
France


Elmar Kirches
Department of Neuropathology
Otto-von-Guericke University
Magdeburg
Germany




Advertisement


Webmaster Contact: urooj@benthamscience.org Copyright © 2014 Bentham Science