Frontiers in Clinical Drug Research – Anti Allergy Agents

Volume 2

by

Atta-ur-Rahman

DOI: 10.2174/97816810815951160201
eISBN: 978-1-68108-159-5, 2016
ISBN: 978-1-68108-160-1
ISSN: 2452-3194 (Print)
ISSN: 2214-6938 (Online)



Recommend this eBook to your Library

Indexed in: EBSCO.

Frontiers in Clinical Drug Research - Anti-Allergy Agents is an exciting eBook ...[view complete introduction]

Table of Contents

Preface

- Pp. i

Atta-ur-Rahman

Download Free

List of Contributors

- Pp. iii-iv (2)

Atta-ur-Rahman

Download Free

Inflammatory Mediators and Neuromodulators: Targeting in Asthma and Chronic Obstructive Pulmonary Disease

- Pp. 3-44 (42)

Soledad Gori, Julieta María Alcain, Gabriela Salamone and Mónica Vermeulen

View Abstract Purchase Chapter

Allergic Asthma Pathogenesis and Antioxidant Therapy

- Pp. 45-79 (35)

Li Zuo, Lei Ni and Chia-Chen Chuang

View Abstract Purchase Chapter

Antioxidants as a Therapeutic Option in Inflammatory Liver Diseases with a Metabolic Origin

- Pp. 80-105 (26)

María de Fátima Higuera-de la Tijera and Alfredo Israel Servín-Caamaño

View Abstract Purchase Chapter

Medical Treatment of Allergic Rhinitis

- Pp. 106-121 (16)

Tolgahan Catli, Deniz Hanci and Cemal Cingi

View Abstract Purchase Chapter

Nothing to be Sneezed at: Th2 Cytokines as Novel Therapeutic Targets for the Production of Anti- Allergy Agents

- Pp. 122-148 (27)

Nayyar Ahmed and Cenk Suphioglu

View Abstract Purchase Chapter

Peripheral and Central Inflammation Caused by Neurogenic and Immune Systems and Anti- Inflammatory Drugs

- Pp. 149-206 (58)

Akio Hiura, Hiroshi Nakagawa, Eiichi Kumamoto, Tao Liu, Tsugumi Fujita and Chang-Yu Jiang

View Abstract Purchase Chapter

Anti-Allergy Agents, from Past to Future

- Pp. 207-243 (37)

Howayda M. Hassoba, Ranya M. Hassan and Mohamed A. Mandour

View Abstract Purchase Chapter

Subject Index

- Pp. 244-252 (9)

Atta-ur-Rahman

Download Free

Preface

The second volume of Frontiers in Clinical Drug Research – Anti Allergy Agents comprises seven comprehensive chapters covering various aspects of clinical drugs used for treating the allergic conditions contributed by leading researchers in the field.

In the first chapter, Vermeulen and colleagues focus mainly on the commonly occurring pulmonary tract ailments. They discuss the inflammatory mediators and neuromodulators that play a significant role in these diseases. They have provided a comprehensive overview of the novel therapeutic targets; histamine, acetylcholine and cysteinyl-leukotrienes, with emphasis on the advantages and shortcomings of the clinical trials carried out. In the second chapter, Zuo et al. discuss the various antioxidants available from supplements and diet that are potentially useful for the treatment and prevention of asthma. The pathogenesis of allergic asthma and its correlation with inflammation and ROS/OS are presented. In chapter 3, Higuera-de la Tijera and Servín- Caamaño highlight the role of anti-oxidants in managing the inflammatory liver diseases with a metabolic origin, for minimizing the oxidative stress.

Cingi and colleagues review the management therapies for allergic rhinitis in chapter 4. The different pharmacological therapies and recent advancements in the field of Allergic Rhinitis (AR) are presented including the treatment of pediatric AR patients. In chapter 5, Suphiglu and Ahmed present a comprehensive overview on Th2 cytokines as the new therapeutic target for the development of anti-allergic agents. They have highlighted the important targets, cytokines IL-4 and IL-13 and their receptors, that are key factors in the allergic cascade.

Nakagawa et al., in chapter 6 present the role of algogenic substances (chemicals and natural products), their receptors, and anti-inflammatory drugs interrupting receptors, channels, and intracellular messengers, mainly in peripheral sensitization. They also discuss thermosensing TRP channels and IL-1β. TRP channels are closely correlated with itching and inflammation. In the final chapter of this eBook, Hassoba and colleagues present a comprehensive overview on allergic disorders and anti-allergy agents from almost all aspects in light of various contributions.

I would like to thank all the contributors for their painstaking efforts in putting together an outstanding collections of reviews that comprehensively cover various aspects of this important field. I am also grateful to the excellent team of Bentham Science Publishers, especially Dr. Faryal Sami and Mr. Shehzad Naqvi led by Mr. Mahmood Alam, Director Bentham Science Publishers.

Atta-ur-Rahman, FRS
Honorary Life Fellow
Kings College
University of Cambridge
Cambridge
UK

List of Contributors

Editor(s):
Atta-ur-Rahman FRS
University of Cambridge
UK




Contributor(s):
Akio Hiura
Department of Oral Histology, School of Dentistry, Department of Pediatric Dentistry
Tokushima University Hospital, University of Tokushima
3-18-15 Kuramato cho
Tokushima, 770-8504
Japan


Alfredo Israel Servín-Caamaño
Gastroenterology Department and Internal Medicine Department
Unit 108, “Hospital General de México, Dr. Eduardo Liceaga”
Mexico City
Mexico


Cemal Cingi
Department of Otorhinolaryngology, Faculty of Medicine
Osmangazi University
Eskisehir
Turkey


Cenk Suphioglu
NeuroAllergy Research Laboratory (NARL), School of Life and Environmental Sciences
aculty of Science, Engineering and Built Environment, Deakin University
75 Pigdons Road, Geelong
Victoria 3216
Australia


Chang-Yu Jiang
Allergy, Asthma and Sports Unit
Saga Medical School, 5-1-1 Nabeshima
Saga 849-8501
Japan


Chia-Chen Chuang
Radiologic Sciences and Respiratory Therapy Division, School of Health and Rehabilitation Sciences
Davis Heart and Lung Research Institute, The Ohio State University College of Medicine
The Ohio State University Wexner Medical Center
Columbus, OH 43210
USA


Deniz Hancı
Department of Otorhinolaryngology
Liv Hospital
Istanbul


Eiichi Kumamoto
Department of Physiology
Saga Medical School
5-1-1 Nabeshima
Saga, 849-8501
USA


Gabriela Salamone
Laboratorio de Células Presentadoras de Antígeno y Respuesta Inflamatoria, IMEX-CONICET
Academia Nacional de Medicina, Buenos Aires
Argentina and Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET)
Argentina


Hiroshi Nakagawa
Department of Pediatric Dentistry
Tokushima University Hospital, University of Tokushima
3-18-15 Kuramato cho
Tokushima, 770-8504
Japan


Howayda M. Hassoba
Clinical Immunology Unit, Clinical Pathology Department
Faculty of Medicine, Suez Canal University
Egypt


Julieta María Alcain
Laboratorio de Células Presentadoras de Antígeno y Respuesta Inflamatoria, IMEX-CONICET
Academia Nacional de Medicina, Buenos Aires
Argentina


Lei Ni
Radiologic Sciences and Respiratory Therapy Division, School of Health and Rehabilitation Sciences
Davis Heart and Lung Research Institute, The Ohio State University College of Medicine
The Ohio State University Wexner Medical Center
Columbus
OH, 43210
USA
/
Department of Pulmonary Medicine, Ruijin Hospital
School of Medicine, Shanghai Jiao Tong University
Shanghai, 200025
China


Li Zuo
Radiologic Sciences and Respiratory Therapy Division, School of Health and Rehabilitation Sciences
Davis Heart and Lung Research Institute, The Ohio State University College of Medicine
The Ohio State University Wexner Medical Center
Columbus
OH, 43210
USA


María de Fátima Higuera-de la Tijera
Gastroenterology Department and Internal Medicine Department
Unit 108, “Hospital General de México, Dr. Eduardo Liceaga”
Mexico City
Mexico


Mohamed A. Mandour
Clinical Immunology Unit, Clinical Pathology Department
Faculty of Medicine, Suez Canal University
Egypt


Mónica Vermeulen
Laboratorio de Células Presentadoras de Antígeno y Respuesta Inflamatoria, IMEX-CONICET
Academia Nacional de Medicina, Buenos Aires
Argentina and Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET)
Argentina


Nayyar Ahmed
NeuroAllergy Research Laboratory (NARL), School of Life and Environmental Sciences
aculty of Science, Engineering and Built Environment, Deakin University
75 Pigdons Road, Geelong
Victoria 3216
Australia


Ranya M. Hassan
Clinical Immunology Unit, Clinical Pathology Department
Faculty of Medicine, Suez Canal University
Egypt


Soledad Gori
Laboratorio de Células Presentadoras de Antígeno y Respuesta Inflamatoria, IMEX-CONICET
Academia Nacional de Medicina, Buenos Aires
Argentina and Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET)
Argentina


Tao Liu
Center for Laboratory Medicine
the First Affiliated Hospital of Nanchang University
Nanchang, 330006
China
/
Department of Pediatrics
the First Affiliated Hospital of Nanchang University
Nanchang, 330006
China


Tolgahan Catli
Department of Otorhinolaryngology
Bozyaka Teaching and Research Hospital
Izmir
Turkey


Tsugumi Fujita
Department of Physiology
Saga Medical School, 5-1-1 Nabeshima
Saga 849-8501
Japan




Advertisement



Webmaster Contact: info@benthamscience.org Copyright © 2017 Bentham Science