Frontiers in Clinical Drug Research - Alzheimer Disorders

Volume 6

by

Atta-ur-Rahman, FRS

DOI: 10.2174/97816810833911170601
eISBN: 978-1-68108-339-1, 2017
ISBN: 978-1-68108-340-7
ISSN: 2451-8743 (Print)
ISSN: 2214-5168 (Online)



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Frontiers in Clinical Drug Research - Alzheimer Disorders is a book series concerned with Alzheimer'...[view complete introduction]

Table of Contents

Preface

- Pp. I

Atta -ur- Rahman

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List of Contributors

- Pp. II

Atta -ur- Rahman

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The Treatment of Brain Inflammation in Alzheimer’s Disease. Can Traditional Medicines Help?

- Pp. 1-19 (19)

James David Adams

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Stem Cell Strategies for the Modeling and Therapy of Alzheimer’s Disease

- Pp. 20-55 (36)



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Retinal Neurodegeneration in Alzheimer’s Disease

- Pp. 56-86 (31)

L. Guo, M. Pahlitzsch, F. Javaid and M. F. Cordeiro

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Pathophysiology of Alzheimer Disease: Current Drug Therapy

- Pp. 87-109 (23)

Sumeet Gupta and Vikas Jhawat

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Biological Mass Spectrometry for Diagnosis of Alzheimer's Disease

- Pp. 110-126 (17)

Hani Nasser Abdelhamid and Hui-Fen Wu

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The Structure-Activity Relationship of Melanin as a Source of Energy Defines the Role of Glucose to Biomass Supply Only, Implications in the Context of the Failing Brain

- Pp. 127-153 (27)

Arturo Solís Herrera

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Neuro-protective Properties of the Fungus Isaria japonica: Evidence from a Mouse Model of Agedrelated Degeneration

- Pp. 154-186 (33)

Koichi Suzuki, Masaaki Tsushima, Masanobu Goryo, Tetsuro Shinada, Yoko Yasuno, Eiji Nishimura, Yasuo Terayama, Yuki Mori and Yoshichika Yoshioka

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Subject Index

- Pp. 187-196 (10)

Atta -ur- Rahman

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Preface

The book series, “Frontiers in Clinical Drug Research – Alzheimer Disorders”, is intended to present the important advancements in the field in the form of cutting edge reviews written by experts. Volume 6 of this eBook series is a compilation of seven well written chapters contributed by prominent researchers in the field. It includes the treatment of brain inflammation, stem cell strategies, retinal neurodegeneration, pathophysiology of Alzheimer disease, and a number of other related areas.

Chapter 1 by Adams discusses the use of plant medicines as an alternative treatment to decrease the progression of Alzheimer’s disease (AD). In chapter 2, Haigang Gu describes the recent progress of stem cell strategies for AD modeling and therapy. Cordeiro et al. in chapter 3 focus on the retinal neurodegeneration in AD. The pathological similarities between AD and eye diseases are also discussed. In Chapter 4, Gupta & Jhawat highlight the pathophysiology of Alzheimer disease with respect to the current drug therapy.

In chapter 5, Abdelhamid and Wu present the use of biological mass spectrometry for the diagnosis of Alzheimer’s disease. This review also highlights the recent developments in disease diagnosis using mass spectrometry. Chapter 6 by Herrera emphasizes the structure-activity relationship of melanin as a source of energy. The last chapter by Suzuki et al., discusses the neuro-protective properties of the fungus Isaria japonica (IJ). The results showed that products derived from IJ may prevent or decrease the impact of dementia, especially AD.

The 6th volume of this book series represents the results of a huge amount of work by many eminent researchers. I am grateful to the authors for their excellent contributions. I would also like to express my gratitude to the editorial staff of Bentham Science Publishers, particularly Mr. Mahmood Alam (Director Publication), Mr. Shehzad Naqvi (Senior Manager Publications) and Ms. Fariya Zulfiqar (Assistant Manager Publications) for their hard work and persistent efforts.

Prof. Atta-ur-Rahman, FRS
Kings College
University of Cambridge
Cambridge
UK

List of Contributors

Editor(s):
Atta-ur-Rahman, FRS
Kings College, University of Cambridge
Cambridge
UK




Contributor(s):
Arturo Solís Herrera
Human Photosynthesis® Research Center
Sierra del Laurel, 212, Bosques del Prado Norte
CP 20127, Aguascalientes
México


Eiji Nishimura
Graduate School of Science
Osaka City University
Osaka
Japan


F. Javaid
Glaucoma & Retinal Degeneration Research Group
Visual Neurosciences, UCL Institute of Ophthalmology, Bath Street
London, EC1V 9EL
UK


Haigang Gu
Department of Pediatrics
Northwestern University Feinberg School of Medicine, Lurie Children's Hospital Research Center
Chicago, IL 60614
USA


Hani Nasser Abdelhamid
Department of Chemistry
Assuit University
Assuit, 71515
Egypt


Hui-Fen Wu
Department of Chemistry and Center for Nanoscience and Nanotechnology
National Sun Yat-Sen University
Kaohsiung, 70, Lien-Hai Road, Kaohsiung, 80424
Taiwan
/
School of Pharmacy, College of Pharmacy
Kaohsiung Medical University
Kaohsiung, 807
Taiwan
/
Institue of Medical Science and Technology
National Sun Yat-Sen University
Kaohsiung, 70, Lien-Hai Road, Kaohsiung, 80424
Taiwan
/
Doctoral Degree Program in Marine Biotechnology
National Sun Yat-Sen University and Academia Sinica
Kaohsiung, 80424
Taiwan


James David Adams
School of Pharmacy
University of Southern California, 1985 Zonal Avenue
Los Angeles, CA 90089
USA


Koichi Suzuki
Organization for Research Promotion
Iwate University
Morioka, Iwate
Japan


L. Guo
Glaucoma & Retinal Degeneration Research Group
Visual Neurosciences, UCL Institute of Ophthalmology, Bath Street
London, EC1V 9EL
UK


M. Pahlitzsch
Glaucoma & Retinal Degeneration Research Group
Visual Neurosciences, UCL Institute of Ophthalmology, Bath Street
London, EC1V 9EL
UK


M.F. Cordeiro
Glaucoma & Retinal Degeneration Research Group
Visual Neurosciences, UCL Institute of Ophthalmology, Bath Street
London, EC1V 9EL
UK
/
Western Eye Hospital
Imperial College Healthcare Trust
London
UK


Masaaki Tsushima
Organization for Research Promotion
Iwate University
Morioka, Iwate
Japan


Masanobu Goryo
Faculty of Agriculture
Iwate University
Morioka, Iwate
Japan


Sumeet Gupta
Department of Pharmacology, M. M. College of Pharmacy
M. M. University
Mullana, (Ambala), Haryana
India


Tetsuro Shinada
Graduate School of Science
Osaka City University
Osaka
Japan


Vikas Jhawat
Department of Pharmacology, M. M. College of Pharmacy
M. M. University
Mullana, (Ambala), Haryana
India


Yasuo Terayama
Division of Neurology and Gerontology, Department of Internal Medicine
Iwate Medical University
Morioka, Iwate
Japan


Yoko Yasuno
Graduate School of Science
Osaka City University
Osaka
Japan


Yoshichika Yoshioka
Biofunctional Imaging Laboratory, Immunology Frontier Research Center
Osaka University
Osaka
Japan


Yuki Mori
Biofunctional Imaging Laboratory, Immunology Frontier Research Center
Osaka University
Osaka
Japan




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