Chemoinformatics: Directions Toward Combating Neglected Diseases

by

Teodorico C. Ramalho

DOI: 10.2174/97816080518301120101
eISBN: 978-1-60805-183-0, 2012
ISBN: 978-1-60805-502-9



Indexed in: Scopus, EBSCO.

Low-income populations in developing regions of Africa, Asia and the Americas have been particularly injured by a group of tropical in...[view complete introduction]
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An Overview of Tropical Parasitic Diseases: Causative Agents, Targets and Drugs

- Pp. 174-196 (23)

Carlton Anthony Taft and Carlos Henrique Tomich de Paula da Silva

Abstract

There is a need for improved treatments for diseases including protozoan parasitic diseases, such as chagas, malaria, trypanosomiasis, leishmaniasis, onchocerciasis, schistosomiasis, filariasis, toxoplasmosis, cryptosporidiosis, filardiasis and giardiasis. The existing chemotherapy for these diseases is not sufficiently effective due to factors such as toxicity, drug resistance and different strain sensitivities. New chemotherapies are needed to help in the control and prevention of these parasitic diseases.

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