Inositol & its Phosphates: Basic Science to Practical Applications

by

A.K.M. Shamsuddin, Guang-Yu Yang

eISBN: 978-1-68108-007-9, 2015
ISBN: 978-1-68108-008-6



Indexed in: EBSCO.

Inositol and its phosphates are ubiquitous across most life forms, wherein they play important roles in cellular integrity and functio...[view complete introduction]
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Clinical Studies of Human Cancer Treatment

- Pp. 107-116 (10)

A.K.M. Shamsuddin and Guang-Yu Yang

Abstract

Despite compelling experimental evidence of the efficacy of InsP<sub>6</sub> + inositol as an anticancer cocktail, there has been very limited enthusiasm for clinical studies of cancer prevention and/or therapy. Notwithstanding this lack of interest, results from the handful of clinical studies are extremely encouraging. Myo-inositol with or without InsP<sub>6</sub> has shown to be effective in preventing precancerous lesions of lung cancer. Experimentally, InsP<sub>6</sub> acts synergistically with standard chemotherapeutic drugs such as doxorubicin and tamoxifen; emerging clinical data support that. InsP<sub>6</sub> + inositol available as dietary supplement has been reported to cause abrogation of breast, lung and colorectal cancers, with or without standard therapies; reduce chemotherapyinduced negative side-effects and provide a better quality of life.

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