Topics in Anti-Cancer Research

Volume 6

by

Atta-ur-Rahman / Khurshid Zaman

DOI: 10.2174/97816810845581170601
eISBN: 978-1-68108-455-8, 2017
ISBN: 978-1-68108-456-5
ISSN: 2468-5860 (Print)
ISSN: 2213-3585 (Online)



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Indexed in: Chemical Abstracts, Ulrich's Periodicals Directory.

Topics in Anti-Cancer Research covers important advances on both experimental (preclinical) and clinical cancer resea...[view complete introduction]
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Table of Contents

Foreword

- Pp. i
Atta-ur- Rahman and Khurshid Zaman
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Introduction

- Pp. ii
Atta-ur- Rahman and Khurshid Zaman
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List of Contributors

- Pp. iii-iv (2)
Atta-ur- Rahman and Khurshid Zaman
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Targeting Polyunsaturated Fatty Acid Metabolism in Colorectal Cancer Therapy: A Review of Recent Patents

- Pp. 1-30 (30)
Arkadiusz Michalak, Paula Mosińska and Jakub Fichna
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Microtubules as Anti-Cancer Drug Targets

- Pp. 31-74 (44)
Biswa P. Chatterji, Needa N. Bagban and Riddhi I. Bhavsar
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Effects of Inflammation, Mitochondria and Energy Metabolism in the Heart due to Cancer

- Pp. 75-92 (18)
Thomas G. Ikonomidis, Timothy C. Tan and Patsie Polly
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Chalcone and Their Derivatives as Anticancer Agents

- Pp. 93-113 (21)
Zahoor A. Wani and Suaib Luqman
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Regulation/Inhibition of Human Lactate Dehydrogenase A: An Innovative and Potential Approach for Anti-Cancer Drugs Development

- Pp. 114-142 (29)
Vinit Kumar, Atul Kumar and Reshma Rani
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Cancer Chemo-Immunotherapeutics

- Pp. 143-177 (35)
Muzammal Hussain and Jiancun Zhang
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Recent Advances and Challenges in microRNABased Cancer Therapeutics

- Pp. 178-210 (33)
Amjad Ali, Faryal M. Awan, Aqsa Ikram and Shifa T. Ashraf
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Author Index

- Pp. 211
Atta-ur- Rahman and Khurshid Zaman
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Subject Index

- Pp. 212-220 (9)
Atta-ur- Rahman and Khurshid Zaman
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Foreword

The sixth volume of Topics in Anti-Cancer Research presents some exciting contributions in frontier areas of anti-cancer research. These include the role of microtubules for the treatment of various cancers, novel chemoimmunotherapy drug combinations & methods in clinical studies/trial and current studies in targeting polyunsaturated fatty acids (PUFAs) in the treatment of colorectal cancer. Natural and synthetic chalcones and their derivatives that have shown potent anticancer activity against a number of cancer cell lines and murine tumor models are discussed. The discovery of selective small-molecule hLDH-A inhibitors and LDH-based approaches in the progress of anticancer therapy are also presented. Recent advances in microRNA-based cancer therapeutics for the treatment of cancer are presented. The role of inflammation in chemotherapy-induced neuromuscular effects and the side effects and recent relevant patents for beneficial approaches to improve heart failure cases due to inflammation, mitochondria and energy metabolism in cancer cachexia are also covered. It is hoped that the present volume will be found useful by a large number of scientists working in this field.

The editors are thankful to the authors for their excellent contributions and to the reviewers for their in -depth comprehensive comments for the improvement of chapters. We are also grateful to Mr. Mahmood Alam, Mrs. Rafia Rehan and other colleagues for their support and assistance in the finalization of this volume.

Atta-ur-Rahman, FRS
International Center for Chemical and Biological Sciences
University of Karachi
Karachi 75270
Pakistan

Khurshid Zaman
Honorary Editor
Bentham Science Publishers


List of Contributors

Editor(s):
Atta-ur-Rahman / Khurshid Zaman
University of Cambridge
UK
/
Bentham Science Publishers
USA




Contributor(s):
Ali, Amjad
Atta-ur-Rahman School of Applied Biosciences (ASAB)
National University of Sciences and Technology (NUST)
H-12 Islamabad
PakistanEmail: amjaduni@gmail.com; amjad.ali@asab.nust.edu.pk


Ashraf, Shifa T.
Atta-ur-Rahman School of Applied Biosciences (ASAB)
National University of Sciences and Technology (NUST)
H-12 Islamabad
PakistanEmail: stariq.asab@gmail.com


Awan, Faryal M.
Atta-ur-Rahman School of Applied Biosciences (ASAB)
National University of Sciences and Technology (NUST)
H-12 Islamabad
PakistanEmail: faryal_mehwish@yahoo.com


Bagban, Needa N.
Department of Biotechnology
St. Xavier’s College (Autonomous)
Mumbai- 400001
IndiaEmail: neebagban@gmail.com


Bhavsar, Riddhi I.
Department of Biotechnology
St. Xavier’s College (Autonomous)
Mumbai- 400001
IndiaEmail: riddhibhavsar2@gmail.com


Chatterji, Biswa P.
Department of Biotechnology
St. Xavier’s College (Autonomous)
Mumbai- 400001
IndiaEmail: biswaprasun@gmail.com


Fichna, Jakub
Department of Biochemistry
Faculty of Medicine, Medical University of Lodz
Lodz
PolandEmail: jakub.fichna@umed.lodz.pl


Muzammal, Hussain
Institutes of Biomedicine and Health
Chinese Academy of Sciences, 190 Kaiyuan Avenue, Science Park
Guangzhou, 510530, P.R
ChinaEmail: muzammal@gibh.ac.cn


Ikonomidis, Thomas G.
Mechanisms of Disease and Translational Research Group
Department of Pathology, School of Medical Sciences, University of New South Wales
Sydney 2052
AustraliaEmail: thomasikono@gmail.com


Ikram, Aqsa
Atta-ur-Rahman School of Applied Biosciences (ASAB)
National University of Sciences and Technology (NUST)
H-12 Islamabad
PakistanEmail: aqsa_ikram@yahoo.com


Kumar, Vinit
Amity Institute of Molecular Medicine and Stem Cell Research
Amity University
Noida 201313
IndiaEmail: vkumar25@amity.edu


Kumar, Atul
Amity Institute of Engineering & Technology
Amity University
Greater Noida 201313
IndiaEmail: atul206@gmail.com


Luqman, Suaib
CSIR-Central Institute of Medicinal and Aromatic Plants
Lucknow-226015
Uttar Pradesh
IndiaEmail: s.luqman@cimap.res.in


Michalak, Arkadiusz
Department of Biochemistry
Faculty of Medicine, Medical University of Lodz
Lodz
PolandEmail: arkadiusz.michalak.lek@gmail.com


Mosińska, Paula
Department of Biochemistry
Faculty of Medicine, Medical University of Lodz
Lodz
PolandEmail: paula.mosinska@gmail.com


Polly, Patsie
Mechanisms of Disease and Translational Research Group
Department of Pathology, School of Medical Sciences, University of New South Wales
Sydney 2052
AustraliaEmail: patsie.polly@unsw.edu.au


Rani, Reshma
Amity Institute of Biotechnology
Amity University
Noida 201313
IndiaEmail: reshudcy@gmail.com; rrani@amity.edu


Tan, Timothy C.
Western Clinical School and Westmead Hospital
Westmead
New South Wales
AustraliaEmail: timothy.tan9@gmail.com


Wani, Zahoor A.
National Postdoctoral Fellow at CSIR-Central Institute of Medicinal and Aromatic Plants
Lucknow-226015
Uttar Pradesh
IndiaEmail: zahoorwani5@gmail.com


Zhang, Jiancun
Institutes of Biomedicine and Health
Chinese Academy of Sciences, 190 Kaiyuan Avenue, Science Park
Guangzhou, 510530, P.R
ChinaEmail: zhang_jiancun@gibh.ac.cn




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