Frontiers in Clinical Drug Research -CNS and Neurological Disorders

Volume 5

by

Atta-ur-Rahman

DOI: 10.2174/97816810858521170501
eISBN: 978-1-68108-585-2, 2017
ISBN: 978-1-68108-586-9
ISSN: 2451-8883 (Print)
ISSN: 2214-7527 (Online)



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Table of Contents

Preface

- Pp. i
Atta-ur- Rahman
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List of Contributors

- Pp. ii-iii (2)
Atta-ur- Rahman
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Drug Treatment for Spinal Cord Injury

- Pp. 1-33 (33)
Jason H. Oh and Hiroyuki Yoshihara
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Essential Tremor: The Current State and Challenges

- Pp. 34-73 (40)
Martin Kronenbuerger and Zoltan Mari
View Abstract Purchase Chapter

Natural Products for the Treatment of Alzheimer’s Disease: Present and Future Expectations

- Pp. 74-170 (97)
Fernanda Rodriguez-Enriquez, Iria Torres and Dolores Vina
View Abstract Purchase Chapter

Pain Management Strategies: Some Uses of Antidepressant Medications and Non- Pharmacological Approaches

- Pp. 171-183 (13)
Kathy Sexton-Radek, Antoine Chami and Alissa Rubinfeld
View Abstract Purchase Chapter

Biosensors for Detection of Neurotransmitters and Neurodegenerative Related Diseases

- Pp. 184-210 (27)
Gennady A. Evtugyn, Tibor Hianik, Georgia-Paraskevi Nikoleli and Dimitrios P. Nikolelis
View Abstract Purchase Chapter

NMDA Receptor as a Molecular Target for Central Nervous System Disorders: The Advances and Contributions of Molecular Modeling

- Pp. 211-249 (39)
Marcos Vinicius Santana, Helena Carla Castro and Paula Alvarez Abreu
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Therapeutic Potential of Plant Alkaloids as Antidepressant

- Pp. 250-267 (18)
Haroon Khan
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Subject Index

- Pp. 268-277 (10)
Atta-ur- Rahman
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Preface

Frontiers in Clinical Drug Research - CNS and Neurological Disorders presents the recent developments for the treatment of central nervous system (CNS) and nerve disorders. The book is a valuable resource for pharmaceutical scientists, postgraduate students and researchers seeking updated and critical information for devising research plans in the field of neurology. The chapters are written by eminent authorities in the field. The contents of this volume represent exciting recent researches on spinal cord injury, essential tremor, alzheimer’s disease, pain management, neurotransmitters and neurodegenerative diseases, NMDA receptors, and plant alkaloids as antidepressants.

I hope that the readers will find these reviews valuable and thought provoking so that they may trigger further research in the quest for the new and novel therapies against CNS disorders.

I am grateful for the efforts made by the editorial personnel, especially Mr. Mahmood Alam (Director Publications), and Mr. Shehzad Naqvi (Senior Manager Publications) at Bentham Science Publishers.

Atta-ur-Rahman, FRS
Honorary Life Fellow
Kings College
University of Cambridge
UK

List of Contributors

Editor(s):
Atta-ur-Rahman FRS
Kings College
University of Cambridge
Cambridge
UK




Contributor(s):
Alissa Rubinfeld
Suburban Pulmonary & Sleep Associates
Elmhurst College
North Riverside, IL
USA
/
Chicagoland Advanced Pain Specialists
Westmont, IL
USA
/
The Chicago School of Professional Psychology
Chicago, IL
USA


Antoine Chami
Suburban Pulmonary & Sleep Associates
Elmhurst College
North Riverside, IL
USA
/
Chicagoland Advanced Pain Specialists
Westmont, IL
USA
/
The Chicago School of Professional Psychology
Chicago, IL
USA


Dimitrios P. Nikolelis
Laboratory of Environmental Chemistry, Department of Chemistry
University of Athens
Athens
Greece


Dolores Viña
Center for Research in Molecular Medicine and Chronic Diseases (CIMUS)
University of Santiago de Compostela
Santiago de Compostela
Spain


Fernanda Rodríguez-Enríquez
Center for Research in Molecular Medicine and Chronic Diseases (CIMUS)
University of Santiago de Compostela
Santiago de Compostela
Spain


Gennady A. Evtugyn
Analytical Chemistry Department
Kazan Federal University
Kazan
Russian Federation
/
OpenLab “DNA-Sensors”
Kazan Federal University
Kazan
Russian Federation


Georgia-Paraskevi Nikoleli
Laboratory of Inorganic & Analytical Chemistry, School of Chemical Engineering, Dept. 1, Chemical Sciences
National Technical University of Athens
Athens
Greece


Gino Giannaccini
Department of Pharmacy
University of Pisa
Pisa
Italy


Haroon Khan
Department of Pharmacy
Abdul Wali Khan University
Mardan
Pakistan


Helena Carla Castro
LabiEMol, Laboratório de Antibióticos, Bioquímica, Ensino e Modelagem molecular
Instituto de Biologia, Universidade Federal Fluminense
Niterói, RJ
Brazil


Hiroyuki Yoshihara
State University of New York
University Hospital of Brooklyn
Brooklyn, NY
USA


Iria Torres
Center for Research in Molecular Medicine and Chronic Diseases (CIMUS)
University of Santiago de Compostela
Santiago de Compostela
Spain


Jason H. Oh
State University of New York
University Hospital of Brooklyn
Brooklyn, NY
USA


Kathy Sexton-Radek
Suburban Pulmonary & Sleep Associates
Elmhurst College
North Riverside, IL
USA
/
Chicagoland Advanced Pain Specialists
Westmont, IL
USA
/
The Chicago School of Professional Psychology
Chicago, IL
USA


Laura Betti
Department of Pharmacy
University of Pisa
Pisa
Italy


Lionella Palego
Department of Clinical and Experimental Medicine
University of Pisa
Pisa
Italy


Marcos Vinicius Santana
LabiEMol, Laboratório de Antibióticos, Bioquímica, Ensino e Modelagem molecular
Instituto de Biologia, Universidade Federal Fluminense
Niterói, RJ
Brazil


Martin Kronenbuerger
School of Medicine, Department of Neurology
Johns Hopkins University
Baltimore, MD
USA
/
Department of Neurology
University Medicine Greifswald
Greifswald
Germany


Mohammad K. Siddiqi
Interdisciplinary Biotechnology Unit, A.M.U.
Aligarh
India


Munazza T. Fatima
Department of Biochemistry and Tissue Biology, Institute of Biology
State University of Campinas (UNICAMP)
Campinas, SP
Brazil


Parveen Salahuddin
DISC
Interdisciplinary Biotechnology Unit, A.M.U.
Aligarh
India


Paula Alvarez Abreu
LAMCIFAR, Laboratório de Modelagem Molecular e Pesquisa em Ciências Farmacêuticas
Universidade Federal do Rio de Janeiro
Rio de Janeiro, RJ
Brazil


Rizwan H. Khan
Interdisciplinary Biotechnology Unit, A.M.U.
Aligarh
India


Tibor Hianik
OpenLab “DNA-Sensors”
Kazan Federal University
Kazan
Russian Federation
/
Faculty of Mathematics, Physics and Informatics
Comenius University
Bratislava
Slovakia


Yasser E. Shahein
Molecular Biology Department, Genetic Engineering and Biotechnology Division
National Research Centre
Cairo
Egypt


Zoltan Mari
School of Medicine, Department of Neurology
Johns Hopkins University
Baltimore, MD
USA
/
Cleveland Clinic Lou Ruvo Center for Brain Health
West Bonneville Ave
Las Vegas, NV
USA




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