Melanin, the Master Molecule

by

Arturo Solís Herrera

DOI: 10.2174/97816810865381180101
eISBN: 978-1-68108-653-8, 2018
ISBN: 978-1-68108-654-5



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Melanin is a biological molecule associated with pigmentation in humans and animals. However, melanin has been observed to have other ...[view complete introduction]
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Table of Contents

Preface

- Pp. 1
Arturo Solís Herrera
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Dedication

- Pp. ii
Arturo Solís Herrera
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Introduction

- Pp. iii-ixx (67)
Arturo Solís Herrera
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Intrinsic Chemistry of Melanin: Potential Approaches for Translational Medicine

- Pp. 1-50 (50)
Arturo Solís-Herrera and Sergey Suchkov
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The Cell Bioenergetics Pathways Beyond Glucose and Mitochondria and the Intrinsic Chemistry of Melanin

- Pp. 51-73 (23)
Arturo Solís Herrera, María del Carmen Arias Esparza, Ruth I. Solís Arias, Paola E. Solís Arias and Martha P. Solís Arias
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Water of the Cephalous Spinal Fluid- The Main Source of Energy of the Central Nervous System

- Pp. 74-88 (15)
Arturo Solís-Herrera, Graciela Landín-Miranda, Ruth I. Solís-Arias, Paola E. Solís-Arias, Martha P. Solís-Arias and María del Carmen Arias Esparza
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The Unsuspected Intrinsic Property of Respiratory Pigments to Dissociate, Irreversible, the Water Molecule

- Pp. 89-109 (21)
Arturo Solís Herrera
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The Source of Energy of the Nucleus in Eukaryotic Cell is Molecular Hydrogen and High Energy Electrons

- Pp. 110-121 (12)
Arturo Solís Herrera, Arias Esparza, María del Carmen, Solís Arias Ruth I, Solís Arias Paola E and Solís Arias Martha P
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Mental Illness, Alterations in Ventricle Size, and Human Photosynthesis®

- Pp. 122-134 (13)
Arturo Solís Herrera, María del Carmen Arias Esparza, Ruth Isabel Solís Arias, Paola Eugenia Solís Arias and Martha Patricia Solís Arias
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Age-related Macular Degeneration, the Alzheimers Disease of the Eye and the Intrinsic Property of Melanin to Transform Light Power into Chemical Energy

- Pp. 135-166 (32)
Arturo Solís Herrera, Ruth I. Solís-Arias, Paola E. Solís-Arias and Martha P. Solís-Arias
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Energy Production, the Key Role of the Melanin Molecule in the Human Body: Implications in the Context of Aging

- Pp. 166-185 (20)
Arturo Solís Herrera, María del Carmen Arias Esparza, Ruth Isabel Solís Arias, Paola Eugenia Solís Arias and Martha Patricia Solís Arias
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The Unexpected Role of Melanin as Bio-energetic Molecule and Prof. Szent-gyorgyis Energy Concepts: Hydrogen as Main Source of Energy of Muscle Cell

- Pp. 186-228 (43)
Sergey Suchkov, Arturo Solís-Herrera and Ruth Isabel Solís-Arias
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Subject Index

- Pp. 229-235 (7)
Arturo Solís Herrera
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Preface

This book is the result of more than two decades of research, which began with a simple question: what can we do to try to stop the inexorable advance of the three leading causes of blindness in Mexico and that are also all over the world?

The answer was not simple, because despite my best efforts as an ophthalmologist, my patients were losing vision both for glaucoma, diabetes and macular degeneration by age. And the statistical information at the local level, regional and global showed that the incidence and prevalence of these diseases remained unchanged, which meant that the treatments available, by expensive, heroic, sophisticated or pompous to be called were not result.

Research we propose, initiated in 1990, was only intended to find morphological changes in vessels that emerge and penetrate (arteries and veins, respectively) into the optic nerve head, which can be used as indicators of early disease, enabling early treatment.

Nobody thought that the research would be more fruitful than we could even imagine. Twelve years later, in February 2002, was stunned at the results: the melanin was able to dissociate the water molecule.

At that time I was aware of that the result was important, even I thought that already knew many researchers; so it continued working on developing strategies that would allow me to modulate the activity of melanin, as years before understanding as acted, I had noticed that when melanin appeared to be active, the ocular tissues were in a better State than when melanin seemed "off".

It wasn't until 2005, listening to a speech by the then president Bush, who literally said "We need substances that remove hydrogen from water to enter fully into the era of hydrogen".

And I kept thinking about: because not used melanin? Greener want it? We have it all. I began to read to trying to find the answer, and a few months later I came to the conclusion: do not use it because they have not realized. So I decided to start the procedure of patent.

Arturo Solís Herrera
Human Photosynthesis® Study Center
Sierra del Laurel 212, Colonia Bosques del Prado Norte
Aguascalientes, 20127
México

List of Contributors

Author(s):
Arturo Solís Herrera




Contributor(s):
Arias Esparza
Human Photosynthesis® Study Center
Aguascalientes
México


Arturo Solís Herrera
Human Photosynthesis® Study Center, López Velarde 108, Centro
Aguascalientes 20000
México


Graciela Landín-Miranda
Human Photosynthesis® Study Center, López Velarde 108, Centro
Aguascalientes 20000
México


María del Carmen Arias Esparza
Human PhotosynthesisTM Study Center. Avenida Aguascalientes Norte 607, Pulgas Pandas Sur
Aguascalientes
México; CP 20138


Martha Patricia Solís Arias
Human PhotosynthesisTM Study Center. Avenida Aguascalientes Norte 607, Pulgas Pandas Sur
Aguascalientes
México; CP 20138


Paola E. Solís Arias
Human Photosynthesis® Study Center, López Velarde 108, Centro
Aguascalientes20000
México


Ruth Isabel Solís Arias
Human PhotosynthesisTM Study Center. Avenida Aguascalientes Norte 607, Pulgas Pandas Sur
Aguascalientes
México; CP 20138


Sergey Suchkov
I.M. Sechenov Firts Moscow State Medical University and A.I. Konstantinov Moscow State Medical & Dental University, Moscow, Russia





Reviews

Review 1

Plants and human beings have the same very first reaction as the origin of life utilizing either chlorophyll or melanin, that being the first step in the food and energy chains. This implies that the role of the water and glucose could be redefined – that is to say glucose may just be a source of biomass – and, instead, water might the real source of bioenergy of the eukaryotic cell including neurons.

Melanin is a human energy producing pigment which chiefly belongs to members of the animal kingdom as chlorophyll to the plant kingdom. Both of those chemicals make is possible to burn water to liberate electrons. Melanin is able to absorb the full electromagnetic spectrum. In contrast, chlorophyll just absorbs blue and red light. And, finally, melanin has the intrinsic property to split and reform the water molecule using hydrogen peroxide.

Bioenergy and melanin make an exciting and emerging interdisciplinary topic of discussion that combines translational applications with life sciences. The relevance of these areas can be perceived in our lives every time we go to caregivers to receive preventive, prophylactic or rehabilitative treatment.

This book covers a wide range of aspects and issues related to advances in understanding photosynthesis, melanin biology, bioenergy and translational applications whilst covering profile-related cell bioenergetics pathways, impacts of water of the spinal fluid as the main source of CNS energy, the intrinsic properties of respiratory pigments, the role of eukaryotic nucleus as the only source of energy in human CNS, the importance of the latter in developing a variety of human disorders and ageing. The book consists of valuable scientific contributions divided in logistically united sections. The book brings outputs and results of research and development tasks, often supported by important world or framework programs. Knowing how photosynthesis originated and evolved is essential to obtaining the deep understanding required to yield improvements in bioenergy, practical medicine and the environmental applications.

Advanced methods in quantitative biology, systems biology, and translational applications will certainly improve our understanding of the architecture of the interactome-based networks underlying photosynthesis and will also aid the design of novel regulatory circuits and the predictive power of those technologies. And a detailed understanding of how photosynthetic cells can push the boundaries of extreme-environment existence will also fill important gaps in our current understanding of the potential for oxygen-evolving photosynthesis. In this connection, one of the most attractive and strategic avenues would be technologies that would exploit the properties of melanin – the animal analogue to chlorophyll. The outcome of the approach mentioned would unveil newer generations of photocells (including artificial ones) to absorb a broad spectrum of radiation, and to secure conversion of the latter into electric and, possibly, another forms of energy. The other applications would concern the next step in drug design for developing pharmaceuticals ‘armed’ with therapeutic resources to enhance human ‘photosynthesis’ for securing healthy states and, finally, the wellness. Thus, an overarching continuum of the searching, investigational and exploring modes bridging cellular metabolism with the medical area swill be essential for successfully redesigning photosynthesis to sustainably meet global food and bioenergy demand.

Dr Sergey Suchkov, MD, PhD
Professor in Medicine & Immunology,
Director, Center for Personalized Medicine, Sechenov University,
Chair, Dept for Translational Medicine, Moscow Engineering Physical Institute (MEPhI),
Professor, Dept of Immunology, A.I.Evdokimov Moscow State University of Medicine & Dentistry, Russia



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