Alzheimer's Disease: Pathological and Clinical Findings

Book Series: Recent Advances in Alzheimer Research

Volume 3

by

Blas Gil-Extremera

DOI: 10.2174/97898114051361190301
eISBN: 978-981-14-0513-6, 2019
ISBN: 978-981-14-0512-9
ISSN: 2452-2554 (Print)
ISSN: 2452-2562 (Online)



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Indexed in: Scopus.

Alzheimer's disease is the most frequent cause of dementia that slowly and progressively causes cognitive impairment and profoundly alter...[view complete introduction]
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Table of Contents

Preface

- Pp. i
Blas Gil-Extremera
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List of Contributors

- Pp. ii
Blas Gil-Extremera
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Amyloid Hypothesis in Alzheimer´s Disease

- Pp. 1-15 (15)
Maria Sagrario Manzano Palomo
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Brain Connectivity in Alzheimer’s Disease: From the Disconnection Syndrome to the Search for New Biomarkers

- Pp. 16-33 (18)
Alberto Marcos Dolado, David Lopez Sanz, María Eugenia Lopez García, Miguel Yus Fuertes, Laura Marcos Arribas, Cristina Lopez Mico and Fernando Maestu Unturbe
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Pain and Dementia

- Pp. 34-51 (18)
Enrique Arriola Manchola and Javier Alaba Trueba
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Dysphagia in Alzheimer’s Disease

- Pp. 52-66 (15)
J. Garcia-Verdejo and L. Díaz-Rubia
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Biomarkers for the Diagnosis of Alzheimer’s Disease

- Pp. 67-82 (16)
Francisco J. Barrero Hernandez
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Neuroimaging in Alzheimer’s Disease

- Pp. 83-97 (15)
L. Díaz Rubia and J. García Verdejo
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Palliative Care at the End of Life

- Pp. 98-121 (24)
Alfredo J. Pardo-Cabello
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Nutrition and Alzheimer’s Disease

- Pp. 122-143 (22)
Cristina Fernandez-Garcia
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Treatment and Control of Behavioral and Psychololgical Symptoms

- Pp. 144-162 (19)
Juan Carlos Duran Alonso
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Action of Nurses to Improve Prospective Memory in People Affected by Alzheimer’s

- Pp. 163-172 (10)
Borja González-Morales, Maria del Mar Ponferrada Vivanco, María del Carmen Ruiz-Gonzalez and Jacinto Escobar Navas
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Subject Index

- Pp. 173-179 (7)
Blas Gil-Extremera
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Preface

Alzheimer's disease was named after Dr. Alois Alzheimer (1864-1915) in 1906 who described two important microscopic findings: neuritic plaques and neurofibrillary tangles in the brain of a 55-year old female, who died from dementia. These two lesions are characteristic but not pathognomonic of the disease. Alzheimer’s disease is the most common form of dementia in the Western countries. The origin of the disease is still unclear although it has been demonstrated that ageing in the major risk factor. The management of this neurologic disorder is frustrating since, until now, no specific and curative treatment has been found, and so far, the only possibility to fight against the disease is to try to improve as much as possible the symptoms and the neurologic effects of the disease.

Bentham e-Book Editorial had the courtesy to offer to our research group, the invitation to write and update of the Alzheimer’s disease. Nine specialized neurologists and general physicians whose expertise are based on dementia and old people diseases have participated in this interesting and exciting project.

This book has nine chapters covering different aspects of the disease such as amyloid hypothesis, symptoms, pain, dysphagia, neuroimaging, brain connectivity, treatment, nutrition and palliative care. I believe that this book can be of great interest for students, physicians, internists, and even for patients, and their families.

Finally, I would like to thank all the authors in this book, also Esperanza Velasco Rodríguez for the preparation of the manuscripts, and the Bentham Publishing Editorial that gave us this valuable opportunity.

Blas Gil-Extremera
Department of Medicine,
Universidad de Granada,
Granada,
Spain

List of Contributors

Editor(s):
Blas Gil-Extremera
Department of Medicine
Universidad de Granada
Granada
Spain




Contributor(s):
Alberto Marcos Dolado
Neurology Department
Hospital Clinico San Carlos
Madrid
Spain


Alfredo J. Pardo-Cabello
Department of Internal Medicine
San Cecilio University Hospital
Granada
Spain


Borja González-Morales
Resident Nurse of Mental Health
Hospital Universitario Virgen de las Nieves
Granada
Spain


Cristina Fernández-García
Cognitive Impairment Unit, Neurology Service,
La Moraleja University Hospital
Madrid
Spain


Cristina López Mico
Neurology Department
Hospital Clinico San Carlos
Madrid
Spain


David López Sanz
Neurology Department
Hospital Clinico San Carlos
Madrid
Spain


Enrique Arriola Manchola
Memory and Alzheimer Unit
Matiá Foundation
San Sebastián
Spain


Fernando Maestú Unturbe
Neurology Department
Hospital Clinico San Carlos
Madrid
Spain


Francisco J. Barrero Hernández
Service of Neurology
“San Cecilio” Hospital. University of Granada
Granada
Spain


Javier Alaba Trueba
Member of Dementia Group of the Spanish Society of Geriatrics and Gerontology (SEGG)



J. García Verdejo
Service of Internal Medicine
General Hospital
São Bernardo do Campo
Motril
Spain


Juan Carlos Durán Alonso
Geriatric Medicine Department
“San Juan Grande” Hospital, Jerez de la Frontera
Cádiz
Spain


Jacinto Escobar Navas
President of the Official College of Nursing of Granada
Granada
Spain


L. Díaz Rubia
Department of Radiology
Hospital Clínico San Cecilio
Granada
Spain


Laura Marcos Arribas
Neurology Department
Hospital Clinico San Carlos
Madrid
Spain


Maria Sagrario Manzano Palomo
Neurology Department
Infanta Leonor Hospital
Madrid
Spain


María Eugenia López García
Neurology Department
Hospital Clinico San Carlos
Madrid
Spain


Miguel Yus Fuertes
Neurology Department
Hospital Clinico San Carlos
Madrid
Spain


María del Mar Ponferrada Vivanco
Resident Nurse of Mental Health
Hospital Universitario Virgen de las Nieves
Granada
Spain


María del Carmen Ruiz-González
Resident Nurse of Mental Health
Health & Sciences Technology Park Hospital
Granada
Spain




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