Preface

Nano-carriers are an innovative and promising alternative technology for cancer treatment, which show many advantages over conventional cancer therapies. It provides new opportunities for early detection, improved treatment, and diagnosis of cancer. Currently, available cancer treatments include radiation therapy, targeted therapy, surgery, chemotherapy, radiation therapy, immunotherapy, and some existing symptomatic treatments. The present challenges faced for the treatment of cancer are mainly due to the heterogenicity of some cancers, drug resistance, late diagnosis, few treatment advances for early-stage cancer, non-selectivity of drugs towards cancer cells leading to side effects and many more, which are still in the dark. The development of such ligand decorated nano- carriers modifies the anticancer drug accumulation and distribution, thus producing the best possible therapeutic effects to the cancerous cells that will finally reduce the dose and dosing frequency of the anticancer drug. Nano-drug delivery by various drug delivery systems has emerged as a commanding technology for the treatment of various cancers. Nanotechnology provides new rays of hope for the effective treatment of different types of cancer. Nanotechnology-based drug delivery carriers (NCs), such as nanoparticles, liposomes, dendrimers, polyplexes, solid lipid nano-carriers and many more, offer treatment strategies due to their ability to target cancer cells. Nano-carriers are used for targeted drug delivery of medicaments to the desired site along with their surface modification which has shown their significance in the management of cancer. The book contains thirteen chapters, including an introduction to cancer biology, nanotechnology for cancer treatment: an introduction, potential approaches for delivery of surface decorated nano-carriers in the management of carcinoma, the importance of surface-modified nano-carriers in the management of cancer, Importance of nano-carriers in prostate cancer, Future prospects and challenges in toxicology related to nanoparticles, Nano-carriers and its role in the treatment of breast cancer, the importance of surface-modified nano-carriers in the management of cervical cancer, the importance of nano-carriers in colon cancer, nano-carriers in treatment of head and neck cancer, accounts on nano-carrier system for diagnosis purpose, cancer drug products containing nanomaterials: key regulatory issues and future prospects and challenges in treatment of cancer. Each chapter discusses an introduction to the cancer biology role of nanotechnology, potential approaches for delivery of surface decorated nano-carriers in the management of carcinoma, and cancer drug products containing nanomaterials: key regulatory issues and future prospects and challenges in the treatment of cancer. We hope the book shall be a useful compilation for undergraduate, postgraduate, and doctoral students and researchers working in cancer and drug delivery research, research and development, and national research institutes. We hope to receive feedback, suggestions, and inputs from researchers and students that will help improve the next edition of the book.