Editors: Reza Heidari, M. Mehdi Ommati

Taurine and the Mitochondrion: Applications in the Pharmacotherapy of Human Diseases

eBook: US $79 Special Offer (PDF + Printed Copy): US $127
Printed Copy: US $87
Library License: US $316
ISBN: 978-981-5124-49-1 (Print)
ISBN: 978-981-5124-48-4 (Online)
Year of Publication: 2023

Introduction

Taurine, or 2-aminoethanesulfonic acid, is one of the most abundant sulfur-containing amino acids in the human body. It is found in the heart, brain, retina, and skeletal muscles, and is synthesized in the pancreas. Studies have revealed that taurine is of high physiological importance: it protects against pathologies associated with mitochondrial diseases, and linked processes like aging, metabolic syndrome, cancer, cardiovascular diseases, and neurological disorders. It is also used as a nutritional supplement.

Taurine and the Mitochondrion: Applications in the Pharmacotherapy of Human Diseases explores the significance of taurine in the biology of mitochondria. It also explains its role as a pharmacological agent for treating different diseases. Readers will gain an insight into the crucial role it plays in human physiology and the benefits of taurine supplements.

Topics covered in this reference include

- Synthesis of taurine and its dietary sources

- The Role of taurine in mitochondrial health

- Taurine as a neurotransmitter

- Beneficial effects of taurine in physiological systems such as the reproductive system, renal system, and the gastrointestinal tract

- Hepatoprotective and anti-inflammatory properties of taurine

- The anti-aging promise of taurine supplementation

- Role of taurine supplementation in obesity

Preface

- Pp. i
Reza Heidari, M. Mehdi Ommati
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Dedication

- Pp. ii
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Taurine: Synthesis, Dietary Sources, Homeostasis, and Cellular Compartmentalization

- Pp. 1-21 (21)
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Taurine and the Mitochondrion

- Pp. 22-44 (23)
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Applications of Taurine in the Central Nervous System Disorders Linked with Mitochondrial Impairment

- Pp. 45-75 (31)
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Taurine and the Cardiovascular System: Focus on Mitochondrial-related Pathologies

- Pp. 76-107 (32)
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Taurine and the Liver: A Focus on Mitochondria-related Liver Disease

- Pp. 108-136 (29)
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Taurine as an Anti-aging Compound: Focus on Mitochondria-related Mechanisms

- Pp. 137-173 (37)
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Taurine and Skeletal Muscle Disorders: Highlighting the Mitochondria-dependent Mechanisms

- Pp. 174-199 (26)
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Taurine and the Renal System: Effects on Mitochondrial Function and Energy Metabolism

- Pp. 200-225 (26)
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The Mechanism of Action of Taurine in the Digestive System

- Pp. 226-238 (13)
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The Role of Taurine in the Reproductive System: A Focus on Mitochondria-related Mechanisms

- Pp. 239-273 (35)
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Role of Taurine Supplementation in Obesity: Stimulating Fats to Burn in Cellular Power Plants

- Pp. 274-307 (34)
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The Importance of Appropriate Taurine Formulations to Target Mitochondria

- Pp. 308-327 (20)
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Subject Index

- Pp. 328-332 (5)
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