New Trends in Biomarkers and Diseases Research: An Overview

by

Juan Antonio Vílchez, María Dolores Albaladejo-Otón

DOI: 10.2174/97816810849541170101
eISBN: 978-1-68108-495-4, 2017
ISBN: 978-1-68108-496-1





Biomarkers are any measurable biochemical characteristics of an organism that reflect a particular physiological state. Biomarkers can...[view complete introduction]
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New Research About Biomarkers and Atrial Fibrillation

- Pp. 223-250 (28)

Diana Hernández-Romero, Vanessa Roldán, Mariano Valdés and Francisco Marín

Abstract

Atrial fibrillation (AF) is the most common sustained chronic cardiac arrhythmia in clinical practice, increasing the risk of stroke, thromboembolism and mortality. The pathophysiology of AF is complex, including inflammation, oxidative stress, structural remodeling with apoptosis or fibrosis, leading to remodeling in the atria. However, the underlying mechanisms involved in the development of AF are not fully understood. Biomarkers, mainly determined in peripheral blood may increase our knowledge of the pathophysiology of AF with important implications in the assessment of AF diagnosis, prognosis, or therapy decision-making. The aim of this chapter is to provide an exhaustive overview of the knowledge about classical and novel biomarkers in AF and their implications, diagnostic and therapeutic potential.

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