Editors: Tilak Saha, Manab Deb Adhikari, Bipransh Kumar Tiwary

Recent Trends and The Future of Antimicrobial Agents - Part I

eBook: US $79 Special Offer (PDF + Printed Copy): US $127
Printed Copy: US $87
Library License: US $316
ISBN: 978-981-5079-61-6 (Print)
ISBN: 978-981-5079-60-9 (Online)
Year of Publication: 2022
DOI: 10.2174/97898150796091230101

Introduction

Recent Trends and the Future of Antimicrobial Agents provides a significantly expanded overview of the topic with updated research in a broader context on the development of alternative approaches against microbial infections. This part consists of ten chapters. The first five chapters describe naturally derived antimicrobial compounds such as plant-based antimicrobials (PBAs), enzymes-based and antibody-based antibacterial therapeutic and secondary metabolites from plant endophytes. The book proceeds to provide details about antimicrobials derived from marine microorganisms (bacteria, fungi, actinomycetes, and cyanobacteria) is included to inform readers about effective medications against MDR strains. Specific chapters describe the drug development against protozoans, with one chapter focusing on Plasmodium. Chapter contributors have postulated novel approaches for antimalarial therapeutics. The book also includes an explanation of host target identification and drug discovery with the purpose of informing the reader about the implications in viral biology and how they could be exploited for treating viral diseases. The contents cater to the information needs of professionals and learners in academia, industry and health services who aim to learn the most significant experimental and practical approaches towards finding alternatives to existing antimicrobial therapies.

Audience:

Researchers at the graduate and postgraduate levels, healthcare professionals.

Foreword

The book “Recent Trends and The Future of Antimicrobial Agents” tries to explore various alternatives of multi drug resistant bacteria which are the major causes of therapeutic failure. The book provides various approaches to the solution and each section describes and analyses the approach towards the problem. Research is going on globally on various alternatives to treatment like Plant based antimicrobials, Photodynamic therapies, enzyme based and antibody based antimicrobial approaches, chemical compounds that act as antimicrobial agents, nano-materials which act as antimicrobial agents, probiotic, prebiotic and peptides compounds or agents. The writers have taken up each scenario to make the readers understand about the macro and micro factors associated with the approach.

The book attempts to throw light on the various aspects of the pathogenic multi drug resistant bacteria and takes a wide horizon on the impact of antibiotics on them. The discovery of penicillin paved the way for the antibiotics to become popular but as the bacteria can accumulate on multiple genes making them resistant to a particular drug, similarly the resistance can also be caused by an increased expression of genes responsible for multi-drug efflux pumps forcing out a lot many drugs. Hence the need to develop an alternative strategy is very critical for therapeutic success. The book describes all these scenarios in two subsequent volumes of the title. Volume-1 includes the naturally derived antimicrobial remedies/strategies. The Volume-2 of the same title incorporates the chemical and advanced nanomaterial based strategies along with sustainable antimicrobial strategies viz. use of probiotics and photodynamic therapy. I would like to thank the authors for their dedicated effort and the publishers in converting that effort into a reality. I am sure that the information will be very useful for Clinicians as well as Microbiologists.

Dhrubajyoti Chattopadhyay PhD, F.A.Sc , F.Na.Sc , F.A.Sc.T
Vice Chancellor
Sister Nivedita University
Kolkata